Open Advanced Search

Log in
Enterprise Plans
Sign Up

Log in
Sign Up
Enterprise Plans
Browse
Features
Pricing

DeepDyve

Advanced Search

show/hide query preview

With all of the words or DOIs:

DeepDyve's default query mode: search by keyword or DOI.

With the exact phrase:

Require these words, in this exact order. Do not surround your terms in double-quotes ("") in this field.

With at least one of the words:

Find any of these words, separated by spaces

Without the words:

Exclude each of these words, separated by spaces

With words in the article title:

Search for these terms only in the title of an article

Published between the years:

With the following authors:

Most effective as: LastName, First Name or Lastname, FN

With words in the journal name:

Search for articles published in journals where these words are in the journal name

Reset filters

Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

DeepDyve requires Javascript to function. Please enable Javascript on your browser to continue.

Abl Family Kinases in Development and Disease

Part of the Molecular Biology Intelligence Unit Book Series

DOI: 10.1007/978-0-387-68744-5

ISBN: 978-0-387-36640-1

Publisher: Springer New York - Springer Journals

Jan 1, 2006

1 - 9 of 9 Chapters

LitStream

Chapter 1Mechanisms of Activation of Abl Family Kinases

Hantschel, Oliver; Superti-Furga, Giulio

Pages: 1 –10

[Evidence that has accumulated over the last years points to c-Abl and Arg (ABL1 and ABL2) as being particular forms of the Src family of kinases. Just as much as or even more than the Src kinases, Abl members are built to be able to couple protein-protein interaction with protein tyrosine kinase...
LitStream

Chapter 2Role of Abl Family Kinases in Growth Factor-Mediated Signaling

Pendergast, Ann Marie

Pages: 11 –15

[Constitutive activation of the Abl nonreceptor tyrosine kinases can occur as a result of structural alterations of the Abl1 and Abl2 genes, which leads to the development of leukemia. Tight control of the activities of the endogenous Abl kinases is critical for normal development and maintenance...
LitStream

Chapter 3Regulation of Cell Adhesion Responses by Abl Family Kinases

Tanis, Keith Quincy; Schwartz, Martin Alexander

Pages: 16 –25

[Integrins are cell surface receptors that mediate the interactions of cells with each other and the extracellular matrix. In this chapter, we review experiments indicating that the Abl family of nonreceptor tyrosine kinases, Abl and Arg in vertebrates, are important mediators of cellular...
LitStream

Chapter 4Abl and Cell Death

Wang, Jean Y. J.; Minami, Yosuke; Zhu, Jiangyu

Pages: 26 –47

[The Abl tyrosine kinase contains nuclear-import and -export signals and undergoes nucleo-cytoplasmic shuttling in proliferating cells. The nuclear Abl is activated by DNA damage or tumor necrosis factor to promote cell death through transcription-dependent and -independent mechanisms. The...
LitStream

Chapter 5Regulation of Cytoskeletal Dynamics and Cell Morphogenesis by Abl Family Kinases

Koleske, Anthony J.

Pages: 48 –67

[Abelson (Abl) family nonreceptor tyrosine kinases are essential regulators of cell morphogenesis in developing metazoan organisms. Mutant animals that lack Abl kinases exhibit defects in epithelial and neuronal morphogenesis. In cultured cells, the vertebrate Abl and Abl-related gene (Arg)...
LitStream

Chapter 6Regulation of Cell Motility by Abl Family Kinases

Emami, Shahin; Klemke, Richard L.

Pages: 68 –76

[Cell migration is a highly dynamic process that involves regulation of actin-mediated protrusion of a leading lamellipodia and its adhesion to the extracellular matrix, followed by translocation of the cell body and tail retraction at the rear. The migration machinery is regulated in a highly...
LitStream

Chapter 7Oncogenic Forms of ABL Family Kinases

Ren, Ruibao

Pages: 77 –92

[Disruption of the auto-inhibitory structure of ABL and ARG activates their kinase activity and oncogenic potential. The oncogenic forms of ABL family kinases, v-ABL, BCR-ABL, TEL-ABL, NUP214-ABL, EML1-ABL, and TEL-ARG, are implicated in a variety of hematological malignancies. The tyrosine...
LitStream

Chapter 8Abl Family Kinases in Mammalian Development

Moresco, Eva Marie Y.

Pages: 93 –104

[Abl and Arg nonreceptor tyrosine kinases are widely expressed in mammals, where they contribute to the development of diverse organ and tissue systems. Deletion of abl or arg in mice reveals roles for the kinases in B and T lymphocyte development, neurulation, neuronal dendrite maintenance,...
LitStream

Chapter 9Abelson Family Protein Tyrosine Kinases and the Formation of Neuronal Connectivity

Thompson, Cheryl L.; Van Vactor, David

Pages: 105 –122

[The nervous system is an organ of immense complexity. Neural function and the integration of neural input depend upon the formation of an intricate network of synaptic connections. Building this neural architecture during development involves several aspects of neuronal morphogenesis, from...

results per page

Browse All eBooks

Features

Search and discover articles on DeepDyve, PubMed, and Google Scholar
Read the full-text of open access and premium content
Organize articles with folders and bookmarks
Collaborate on and share articles and folders

Info

Pricing
Enterprise Plans
Browse Journals & Topics
About DeepDyve

Help

Help
Publishers
Contact Us

Sign up for your DeepDyve account now!

Read and print from thousands of top scholarly journals.

System error. Please try again!

Continue with Facebook

By signing up, you agree to DeepDyve’s Terms of Service and Privacy Policy.

Already have an account? Log in

Save Article to Bookmarks

Bookmark this article. You can see your Bookmarks on your DeepDyve Library.

To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.

Subscribe to Journal Email Alerts

To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don’t already have one.

Follow a Journal

To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don’t already have one.

Our policy towards the use of cookies

All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.

cookie policy