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Taurine 7

Part of the Advances in Experimental Medicine and Biology Book Series (volume 643)

Editors: Azuma, Junichi; Schaffer, Stephen W.; Ito, Takashi

DOI: 10.1007/978-0-387-75681-3

ISBN: 978-0-387-75680-6

Publisher: Springer New York - Springer Journals

Jan 1, 2009

1 - 10 of 56 Chapters

LitStream

Effect of Taurine on Protein Kinase C Isoforms: Role in Taurine’s Actions?

Ito, Takashi; Pastukh, Viktor; Solodushko, Viktoriya; Azuma, Junichi; Schaffer, Stephen W.

Pages: 3 –11

[Taurine is generally found to be cytoprotective, diminishing damage resulting from ischemia and from initiators of heart failure. Also linked to similar events in the heart is the protein kinase C (PKC) family, which consists of at least 12 different isoforms. Therefore, we proposed that PKC...
LitStream

Taurine as the Nutritional Factor for the Longevity of the Japanese Revealed by a World-Wide Epidemiological Survey

Yamori, Yukio; Liu, Longjian; Mori, Mari; Sagara, Miki; Murakami, Shigeru; Nara, Yasuo; Mizushima, Shunsaku

Pages: 13 –25

[The initial observation that taurine (T) prevented stroke in stroke-prone spontaneously hypertensive rats (SHRSP) led us to study the effects of T on cardiovascular diseases (CVD), as well as the epidemiological association of T and mortality rates, by using the data from WHO-coordinated...
LitStream

Taurine-Mediated Cardioprotection is Greater When Administered upon Reperfusion than Prior to Ischemia

Miyamoto, Tadaomi-Alfonso; Ueno, Takayuki; Iguro, Yoshihumi; Yotsumoto, Goichi; Fukumoto, Yoshihiro; Nakamura, Kazuo; Sakata, Ryuzo

Pages: 27 –36

[Taurine (TA) administered exogenously before the induction of myocardial ischemia decreases lactic acid production and increases pyruvic acid production during ischemia. It also preserves the activity of GOT, GPT, LDH and CPK during ischemia and enhances recovery of CKMB synthesis as early as 5...
LitStream

Vascular Modulation of Rat Aorta by Taurine

Nishida, Seiichiro; Satoh, Hiroyasu

Pages: 37 –46

[Taurine is found in high concentration in smooth muscle and heart muscle (approximately 10–20 mM). We found that taurine affects NE- and KCl-induced vasoconstriction. The mechanisms regulating these vasoconstrictions mostly involve Ca2+ channels and EDRF(NO). Taurine exerted either a...
LitStream

Modulation by Taurine of Human Arterial Stiffness and Wave Reflection

Satoh, Hiroyasu; Kang, Jangmi

Pages: 47 –55

[Effects of taurine (1000–2000 mg) on hemodynamic function and the arterial pulse wave were investigated for 102 healthy medical and paramedical students. The vascular parameters were generally dependent on aging, with the arterial stiffness parameters, such as baPWV, ABI and AI, are considered...
LitStream

Taurine Suppresses Pressor Response Through the Inhibition of Sympathetic Nerve Activity and the Improvement in Baro-Reflex Sensitivity of Spontaneously Hypertensive Rats

Hano, Takuzo; Kasano, Miki; Tomari, Hiromi; Iwane, Naomi

Pages: 57 –63

[To investigate the effect of taurine on the sympathetic nervous system, I observed pressor responses of perfused mesenteric arteries by electrical stimulation and baro-reflex sensitivity of spontaneously hypertensive rats (SHR/Izm) and control Wistar-Kyoto rats (WKY/Izm) treated with taurine....
LitStream

Beneficial Effect of Taurine Treatment Against Doxorubicin-Induced Cardiotoxicity in Mice

Ito, Takashi; Muraoka, Satoko; Takahashi, Kyoko; Fujio, Yasushi; Schaffer, Stephen W.; Azuma, Junichi

Pages: 65 –74

[Though the administration of taurine is clinically efficacious against heart failure, the mechanism underlying its cardioprotection remains to be established. To provide information on the mechanism, we examined the effects of taurine on doxorubicin (DOX)-induced cardiotoxicity, with an emphasis...
LitStream

Antihypertensive Effect of Taurine in Rat

Hu, Jianmin; Xu, Xingli; Yang, Jiancheng; Wu, Gaofeng; Sun, Changmian; Lv, Qiufeng

Pages: 75 –84

[To investigate the effect of taurine on hypertension, a rat model of hypertension was produced by administering N-nitro-L-arginine methylester (L-NAME) to reduce the levels of the vasodilator, nitric oxide. At the same time that L-NAME was administered, taurine treated animals received either 1%...
LitStream

Attenuating Action of Taurine and Labetalol on Cardiovascular Alterations by Pyridoxal-Isoproterenol, a Vitamin-Drug Interaction with Cardiopathologic Significance

Acharya, Miteshkumar; Lau-Cam, Cesar A.

Pages: 85 –93

[Taking into account the ability of vitamin B6 vitamers (i.e., pyridoxal, pyridoxine, pyridoxamine) to stimulate adrenomedullary catecholamine outflow and biochemical and cardiovascular changes consistent with adrenoceptor stimulation, this study was undertaken in mice to verify the possibility...
LitStream

Tool from Traditional Medicines is Useful for Health-Medication: Bezoar Bovis and Taurine

Takahashi, Kyoko; Azuma, Yuko; Kobayashi, Shizu; Azuma, Junichi; Takahashi, Koichi; Schaffer, Stephen W.; Hattori, Masao; Namba, Tsuneo

Pages: 95 –103

[Bezoar Bovis (BB:dried cattle gallbladder stones) has been used empirically in Asia for over 3000 years to treat heart and liver disorders. Yet its therapeutic potential remains unexplored by Western researchers. The aim of this study has been to clarify the actions of BB on cultured...

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