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Bio-Applications of Nanoparticles

Part of the Advances in Experimental Medicine and Biology Book Series (volume 620)

Editors: Chan, Warren C. W.

DOI: 10.1007/978-0-387-76713-0

ISBN: 978-0-387-76712-3

Publisher: Springer New York - Springer Journals

Sep 1, 2009

1 - 10 of 14 Chapters

LitStream

Chapter 1Synthetic Strategies to Size and Shape Controlled Nanocrystals and Nanocrystal Heterostructures

Cozzoli, P. Davide; Manna, Liberato

Pages: 1 –17

[The recognition of the strongly dimensionality-dependent physical-chemical properties of inorganic matter at the nanoscale has stimulated efforts toward the fabrication of nanostructured materials in a systematic and controlled manner. Surfactant-assisted chemical approaches have now advanced to...
LitStream

Chapter 2Current Approaches for Engineering Proteins with Diverse Biological Properties

Li, Isaac T. S.; Pham, Elizabeth; Truong, Kevin

Pages: 18 –33

[In the past two decades, protein engineering has advanced significantly with the emergence of new chemical and, genetic approaches. Modification and recombination of existing proteins not only produced novel enzymes used commercially and in research laboratories, but furthermore, they revealed...
LitStream

Chapter 3Past, Present, and Future of Gold Nanoparticles

Jennings, Travis; Strouse, Geoffrey

Pages: 34 –47

[Colloidal gold nanoparticles have been around for centuries. Historically, the use of gold nanoparticles has been predominantly found in the work of artists and craftsman because of their vivid visible colors. However, through research, the size, shape, surface chemistry, and optical properties...
LitStream

Chapter 4Multi-Functional Gold Nanoparticles for Drug Delivery

Han, Gang; Ghosh, Partha; Rotello, Vincent M.

Pages: 48 –56

[Multi-functional gold nanoparticles have been demonstrated to be highly stable and versatile scaffolds for drug delivery due to their unique size, coupled with their chemical and physical properties. The ability to tune the surface of the particle provides access to cell-specific targeting and...
LitStream

Chapter 5Quantum Dots for Cancer Molecular Imaging

Gao, Xiaohu; Dave, Shivang R.

Pages: 57 –73

[Quantum dots (QDs), tiny light-emitting particles on the nanometer scale, are emerging as a new class of fluorescent probes for biomolecular and cellular imaging. In comparison with organic dyes and fluorescent proteins, quantum dots have unique optical and electronic properties such as...
LitStream

Chapter 6Carbon Nanostructures as a New High-Performance Platform for MR Molecular Imaging

Hartman, Keith B.; Wilson, Lon J.

Pages: 74 –84

[Over the last several years, great interest has developed in the potential use of carbon nanostructures (C60 fullerenes and nanotubes) in medicine. In some cases, medical agents derived from these materials have demonstrated greater efficacy than existing clinical agents in many imaging and...
LitStream

Chapter 7Magnetic Nanoparticle Assisted Molecular MR Imaging

Jun, Young-wook; Jang, Jung-tak; Cheon, Jinwoo

Pages: 85 –106

[Magnetic nanoparticles exhibit unique nanoscale properties of superparamagnetism and have the potential to be utilized as excellent probes for magnetic resonance imaging (MRI). Especially, clinically benign iron oxide nanoparticles provide good MR probing capability and some of them are...
LitStream

Chapter 8Patterning Metallic Nanoparticles by DNA Scaffolds

Chhabra, Rahul; Sharma, Jaswinder; Liu, Yan; Yan, Hao

Pages: 107 –116

[In order to miniaturize nanoelectronic circuitry and architectures, organizing the nanoelectronic components in deliberately designed complex patterns is desired. Bio-mimetic self-assembly is a possible approach to achieve this goal. Bio-macromolecules can serve as scaffolds to template the...
LitStream

Chapter 9Liposomes in Biology and Medicine

Schwendener, Reto A.

Pages: 117 –128

[Drug delivery systems (DDS) have become important tools for the specific delivery of a large number of drug molecules. Since their discovery in the 1960s liposomes were recognized as models to study biological membranes and as versatile DDS of both hydrophilic and lipophilic molecules....
LitStream

Chapter 10Fluorescent Nanoparticle for Bacteria and DNA Detection

Zhao, Wenjun; Wang, Lin; Tan, Weihong

Pages: 129 –135

[Using bioconjugated dye-doped silica nanoparticles (NPs), we have developed a bioassay for the accurate determination of a single bacterial cell within 20 minutes without any signal amplification or sample enrichment. The antibody-conjugated NPs can specifically and quantitatively detect...

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