DeepDyve eBooks - A Clinician's Pearls and Myths in Rheumatology

Chapter 1Rheumatoid Arthritis

O'Dell, James R.; Smolen, Josef S.; Aletaha, Daniel; Robinson, Dwight R.; St. Clair, E. William

Pages: 1 –13

[Rheumatoid arthritis (RA) affects all ethnic groups. Women are nearly three times more likely than men to develop the disease. The pattern of arthritis typically favors distal and symmetrical involvement. The most commonly involved joints are the wrists, metacarpophalangeal, proximal...

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Chapter 2Rheumatoid Vasculitis

Stone, John H.; Matteson, Eric L.

Pages: 15 –22

[Rheumatoid arthritis (RA) is associated with vasculitis in approximately 1% of patients. Rheumatoid vasculitis (RV) refers specifically to a destructive inflammatory process with protean clinical features that center on the blood vessel wall. The disease strongly resembles polyarteritis nodosa...

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Chapter 3Adult-Onset Still's Disease

Weisman, Michael H.

Pages: 23 –26

[Adult-onset Still's disease (AOSD) was described originally by Eric Bywaters in 1971. AOSD closely resembles systemic-onset juvenile idio-pathic arthritis, a pediatric disorder known originally as Still's disease. An intensely inflammatory, multiorgan system disorder characterized by a...

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Chapter 4Juvenile Idiopathic Arthritis

White, Patience H.; Woo, Patricia; Lindsley, Carol B.

Pages: 27 –32

[Juvenile idiopathic arthritis (JIA) is an umbrella term for a group of persistent arthritides of unknown etiology that affect children under the age of 16, and last for more than 6 weeks (Petty et al. 2004). The clinically defined categories are shown in Table 4.1. The pathogenesis of these...

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Chapter 5Monogenic Autoinflammatory Syndromes

Gattorno, Marco; Martini, Alberto; Goldbach-Mansky, Raphaela; Aubert, Pamela; Ferguson, Polly J.

Pages: 33 –49

[“Autoinflammatory syndromes” is the broad name given to a group of heritable conditions that initially consisted of a group of diseases termed hereditary periodic fever syndromes. Autoinflammatory syndrome is the preferred name for these conditions, because not all of the disorders that have...

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Chapter 6Juvenile Spondyloarthropathy

Cabral, David A.; Tse, Shirley M. L.

Pages: 51 –56

[Juvenile spondyloarthropathy includes both differentiated and undifferentiated forms. The differentiated forms include juvenile ankylosing spondylitis, reactive arthritis, psoriatic arthritis, and arthritis with inflam-matory bowel disease. Enthesitis-related arthritis (ERA) is now the preferred...

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Chapter 7Ankylosing Spondylitis

Braun, Juergen; Yu, David Tak Yan

Pages: 57 –65

[Ankylosing spondylitis (AS) is the prototypical form of the spondyloarthritides, a group of disorders that involves inflammation of the sacroiliac joints, spine, joints, and entheses, as well as extraspinal lesions of the eye, bowel, and heart. Human leukocyte antigen (HLA) B27 is a strong...

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Chapter 8Psoriatic Arthritis

Ritchlin, Christopher; Mody, Elinor; Mease, Philip; Gladman, Dafna D.

Pages: 67 –71

[Psoriatic arthritis (PsA) is a distinctive category of inflammatory arthritis that complicates cutaneous psoriasis. The prevalence of PsA in the general population is estimated to be between 0.3% and 1%, only slightly less common than that of rheumatoid arthritis (RA). PsA is one of the...

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Chapter 9Reactive Arthritis

Inman, Robert D.; Keat, Andrew

Pages: 73 –76

[In reactive arthritis (ReA), exposure to an infectious agent leads to the development of an inflammatory arthritis and other characteristic clinical findings. However, this syndrome occurs in the absence of an ongoing infectious process. About 50% of ReA and undifferentiated oligoarthritis cases...

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Chapter 10Systemic Sclerosis (Scleroderma) and Raynaud’s Phenomenon

Pope, Janet E.; Clements, Philip J.; Furst, Daniel E.; Hummers, Laura K.; Khanna, Dinesh;

Pages: 77 –95

[Systemic sclerosis (scleroderma; SSc) is a chronic con nective tissue disease characterized by inflammation within, and fibrosis of, the skin, vascular abnormalities, visceral damage, and the production of autoantibodies. SSc is divided generally into limited and diffuse forms, based on the...

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A Clinician's Pearls and Myths in Rheumatology

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A Clinician's Pearls and Myths in Rheumatology

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