Open Advanced Search

Log in
Enterprise Plans
Sign Up

Log in
Sign Up
Enterprise Plans
Browse
Features
Pricing

DeepDyve

Advanced Search

show/hide query preview

With all of the words or DOIs:

DeepDyve's default query mode: search by keyword or DOI.

With the exact phrase:

Require these words, in this exact order. Do not surround your terms in double-quotes ("") in this field.

With at least one of the words:

Find any of these words, separated by spaces

Without the words:

Exclude each of these words, separated by spaces

With words in the article title:

Search for these terms only in the title of an article

Published between the years:

With the following authors:

Most effective as: LastName, First Name or Lastname, FN

With words in the journal name:

Search for articles published in journals where these words are in the journal name

Reset filters

Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

DeepDyve requires Javascript to function. Please enable Javascript on your browser to continue.

Electromechanobiology of Cartilage and Osteoarthritis

Part of the Advances in Experimental Medicine and Biology Book Series (volume 1402)

Editors: Connizzo, Brianne K.; Han, Lin; Sah, Robert L.

DOI: 10.1007/978-3-031-25588-5

ISBN: 978-3-031-25587-8

Publisher: Springer International Publishing - Springer Journals

Apr 14, 2023

1 - 10 of 10 Chapters

LitStream

Aggrecan and Hyaluronan: The Infamous Cartilage Polyelectrolytes – Then and Now

Plaas, Anna H. K.; Moran, Meghan M.; Sandy, John D.; Hascall, Vincent C.

Pages: 3 –29

[Cartilagescartilage are unique in the family of connective tissuesTissue in that they contain a high concentration of the glycosaminoglycansGlycosaminoglycan, chondroitinChondroitinsulfateSulfate and keratanKeratan sulfate attached to the core protein of the proteoglycanProteoglycan,...
LitStream

Understanding the Influence of Local Physical Stimuli on Chondrocyte Behavior

Kim, Byumsu; Bonassar, Lawrence J.

Pages: 31 –44

[Investigating the mechanobiology of chondrocytesChondrocyte is challenging due to the complex micromechanical environment of cartilageCartilagetissueTissue. The innate zonalZonal differences and poroelasticPoroelasticPoroelasticity properties of the tissue combined with its heterogeneous...
LitStream

Multiscale In Silico Modeling of Cartilage Injuries

Korhonen, Rami K.; Eskelinen, Atte S. A.; Orozco, Gustavo A.; Esrafilian, Amir; Florea, Cristina; Tanska, Petri

Pages: 45 –56

[Injurious loading of the joint can be accompanied by articular cartilage damage and trigger inflammation. However, it is not well-known which mechanism controls further cartilage degradation, ultimately leading to post-traumatic osteoarthritis. For personalized prognostics, there should also be...
LitStream

In Vitro Models and Proteomics in Osteoarthritis Research

Rydén, Martin; Önnerfjord, Patrik

Pages: 57 –68

[This review summarizes and exemplifies the current understanding of osteoarthritis in vitro models and describes their relevance for new insights in the future of osteoarthritis research. Our friend and highly appreciated colleague, Prof. Alan Grodzinsky has contributed greatly to the...
LitStream

Nanomechanics of Aggrecan: A New Perspective on Cartilage Biomechanics, Disease and Regeneration

Wang, Chao; Kahle, Elizabeth R.; Li, Qing; Han, Lin

Pages: 69 –82

[Articular cartilage is a hydrated macromolecular composite mainly composed of type II collagen fibrils and the large proteoglycan, aggrecan. Aggrecan is a key determinant of the loadLoad bearing and energy dissipation functions of cartilageCartilage. Previously, studies of cartilage...
LitStream

Computational Modelling for Managing Pathways to Cartilage Failure

Miramini, Saeed; Smith, David W.; Gardiner, Bruce S.; Zhang, Lihai

Pages: 83 –93

[Over several decades the perception and therefore description of articular cartilageCartilage changed substantially. It has transitioned from being described as a relatively inert tissue with limited repairRepair capacity, to a tissueTissue undergoing continuous maintenanceMaintenance and even...
LitStream

Gene Delivery to Chondrocytes

Nagelli, Christopher V.; Evans, Christopher H.; De la Vega, Rodolfo E.

Pages: 95 –105

[Delivering genes to chondrocytes offers new possibilities both clinically, for treating conditions that affect cartilage, and in the laboratoryLaboratory, for studying the biology of chondrocytes. Advances in gene therapy have created a number of different viral and non-viral vectors for this...
LitStream

Mechanical Articular Cartilage Injury Models and Their Relevance in Advancing Therapeutic Strategies

Kurz, Bodo; Hart, Melanie L.; Rolauffs, Bernd

Pages: 107 –124

[This chapter details how Alan Grodzinsky and his team unraveled the complex electromechanobiological structure-function relationships of articular cartilage and used these insights to develop an impressively versatile shear and compression model. In this context, this chapter focuses (i) on the...
LitStream

Hip Osteoarthritis: Bench to Bedside Perspective

Kim, Young-Jo

Pages: 125 –133

[OsteoarthritisOsteoarthritis is a major source of painPain, disability, and economic cost worldwide. For nearly a century, there has been a debate about the causes of hip osteoarthritis and the role that structural abnormalities may play as a causative factor. Recent advances in open and...
LitStream

Harnessing Growth Factor Interactions to Optimize Articular Cartilage Repair

Trippel, Stephen B.

Pages: 135 –143

[The failure of cartilage healingHealing is a major impediment to recovery from jointJointdiseaseDisease or trauma. Growth factors play a central role in cellCell function and have been proposed as potential therapeuticTherapeutic agents to promote cartilage repairRepair. Decades of investigation...

results per page

Browse All eBooks

Features

Search and discover articles on DeepDyve, PubMed, and Google Scholar
Read the full-text of open access and premium content
Organize articles with folders and bookmarks
Collaborate on and share articles and folders

Info

Pricing
Enterprise Plans
Browse Journals & Topics
About DeepDyve

Help

Help
Publishers
Contact Us

Sign up for your DeepDyve account now!

Read and print from thousands of top scholarly journals.

System error. Please try again!

Continue with Facebook

By signing up, you agree to DeepDyve’s Terms of Service and Privacy Policy.

Already have an account? Log in

Save Article to Bookmarks

Bookmark this article. You can see your Bookmarks on your DeepDyve Library.

To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.

Subscribe to Journal Email Alerts

To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don’t already have one.

Follow a Journal

To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don’t already have one.

Our policy towards the use of cookies

All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.

cookie policy