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Inflammatory Disorders

Part of the Advances in Experimental Medicine and Biology Book Series (volume 839)

Editors: Pokorski, Mieczyslaw

DOI: 10.1007/978-3-319-10012-8

ISBN: 978-3-319-10011-1

Publisher: Springer International Publishing - Springer Journals

Sep 25, 2014

1 - 9 of 9 Chapters

LitStream

Chapter 51Inhaled Corticosteroids Increase Siglec-5/14 Expression in Sputum Cells of COPD Patients

Wielgat, P.; Mroz, R. M.; Stasiak-Barmuta, A.; Szepiel, P.; Chyczewska, E.; Braszko, J. J.; Holownia, A.

Pages: 1 –5

[Recent studies show that several Siglec receptors, such as Siglec-8 and Siglec-14, may be important therapeutic targets in asthma and COPD. Siglecs are a family of lectins belonging to the immunoglobulin superfamily and recognize sialic acid residues of glycoproteins. Most of Siglecs have...
LitStream

Chapter 43Tregs and HLA-DR Expression in Sputum Cells of COPD Patients Treated with Tiotropium and Formoterol

Holownia, A.; Wielgat, P.; Stasiak-Barmuta, A.; Kwolek, A.; Jakubow, P.; Szepiel, P.; Chyczewska, E.; Braszko, J. J.; Mroz, R. M.

Pages: 7 –12

[Immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) may be involved in the regulation of chronic inflammation in chronic obstructive pulmonary disease (COPD). In this study we analyzed native and activated cell profiles in sputum of 22 stable COPD patients...
LitStream

Chapter 50Inhalation of Macrolides: A Novel Approach to Treatment of Pulmonary Infections

Siekmeier, R.; Hofmann, T.; Scheuch, G.

Pages: 13 –24

[Systemic antibiotic treatment is established for many pulmonary diseases, e.g., cystic fibrosis (CF), bronchiectasis and chronic obstructive pulmonary disease (COPD) where recurrent bacterial infections cause a progressive decline in lung function. In the last decades inhalative administration...
LitStream

Chapter 42Influence of Denture Plaque Biofilm on Oral Mucosal Membrane in Patients with Chronic Obstructive Pulmonary Disease

Przybyłowska, D.; Mierzwińska-Nastalska, E.; Rubinsztajn, R.; Chazan, R.; Rolski, D.; Swoboda-Kopeć, E.

Pages: 25 –30

[Patients with chronic obstructive pulmonary disease (COPD) have the lower airways colonized with pathogenic bacteria in a stable period of the disease and during exacerbations. The etiology of bacterial exacerbations of COPD depends on the underlying disease, the frequency of exacerbations and...
LitStream

Chapter 64Biophysical Activity of Animal-Derived Exogenous Surfactants Mixed with Rifampicin

Kolomaznik, M.; Calkovska, A.; Herting, E.; Stichtenoth, G.

Pages: 31 –39

[Exogenous pulmonary surfactant is a potential delivery system for topical medications via the conducting airways. Due to the sensitivity to inactivation of surfactant, mutual interaction with the shipped drug should be evaluated. Little is known about the interactions between surfactant and...
LitStream

Chapter 48Organic Changes in the Central Nervous System in Children on Chronic Inhaled Corticosteroid Therapy

Michalczuk, M.; Sybilski, A. J.; Piliszek, A.; Walecki, J.

Pages: 41 –45

[Treatment of asthma, the most common chronic respiratory disease in children, includes long-term inhaled corticosteroids (ICS). The purpose of this study was to analyze the impact of chronic inhaled steroids in children with asthma on changes in the central nervous system (CNS). Eleven children...
LitStream

Chapter 27Stem Cell Experiments Moves into Clinic: New Hope for Children with Bronchopulmonary Dysplasia

Pawelec, K.; Gładysz, D.; Demkow, U.; Boruczkowski, D.

Pages: 47 –53

[Bronchopulmonary dysplasia (BPD) is a chronic lung disease with long-term complications that affects mainly preterm born children with low birth weights, especially those treated with mechanical ventilation and oxygen therapy. Successful treatment of BPD could reduce the incidence of other...
LitStream

Chapter 44Soluble Ligand CD40 and Uric Acid as Markers of Atheromatosis in Patients with Obstructive Sleep Apnea

Kosacka, M.; Brzecka, A.; Piesiak, P.; Korzeniewska, A.; Jankowska, R.

Pages: 55 –60

[The aim of the study was to evaluate the risk of atheromatosis in patients with obstructive sleep apnea (OSA), as based on the concentration of the pro-atherogenic soluble CD40L ligand (sCD40L) in relation to the level of uric acid. The serum levels of sCD40L and uric acid were measured in 79...
LitStream

Chapter 45Carotid Artery Intima-Media Thickness in Hypertensive Patients with Obstructive Sleep Apnea

Kostrzewska, M.; Piorunek, T.; Hoffmann, K.; Batura-Gabryel, H.; Cofta, S.

Pages: 61 –66

[In this study we determined the relationship between the severity of obstructive sleep apnea (OSA) and body mass index (BMI), systolic and diastolic blood pressure (SBP, DBP), and carotid intima-media thickness (cIMT) in 30 hypertensive male patients, aged 30–70, with newly diagnosed OSA (15...

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