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[The primary purpose of this chapter is to succinctly present evidence that macrophages are one of the important components within the complex mechanism underlying why lifelong exposure to estrogen is a risk factor for breast cancer. In line with the systems biology theme of this book, this...
[It is now recognized that tumor cells share similarities to stem cells in that they do not have a strong sense of functional identity. In the case of the skin, a mature cell that becomes stem-like no longer has the identity of a skin cell, meaning it changes shape and behaves in ways that make...
[The purpose of this chapter is to provide some insights into the use and misuse of mouse models of cancer. The goal is that this chapter will help investigators better plan their mouse experiments. It also will be helpful in making sense of data that is conflicting or incongruous across...
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