21 - 26 of 26 Chapters
[Appropriate antibiotic therapy in the critically ill requires more specialised considerations than just selecting the most suitable antibiotic and adhering to traditional dosing guidelines. Unfortunately, most of the guideline recommendations are based on research that either underrepresent or...
[Septic shock is a common clinical situation and is associated with a high morbidity and mortality. Appropriate shock approach and support rely on a good understanding of its pathophysiology. Septic shock secondary to abdominal focus presents all the characteristics common to septic shock of...
[The treatment of patients with abdominal sepsis should comply with the internationally accepted guidelines for treating patients with sepsis. These guidelines emphasise the importance of prompt antimicrobial therapy and source control. However, despite timely and appropriate therapy, sepsis...
[Patients suffering from abdominal sepsis are at increased risk of developing intra-abdominal hypertension and abdominal compartment syndrome, which will lead to additional organ dysfunction when left untreated. Patients with severe disease requiring large-volume fluid resuscitation appear to be...
[Venous thromboembolism, pulmonary embolism, and deep venous thrombosis are severe complications of surgical patients. Sepsis is associated with hemostatic changes leading to a subclinical activation of coagulation (hypercoagulability) that may contribute to localized venous thromboembolism....
[Intra-abdominal sepsis can be a challenging pathophysiologic state. There are a lot of misconceptions surrounding nutrition supplementation in patients with intra-abdominal sepsis. Persistent inflammation immunosuppression catabolism syndrome (PICS) is a new phenotype of multiple organ failure...
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