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Metallomics

Part of the Advances in Experimental Medicine and Biology Book Series (volume 1055)

Editors: Arruda, Marco Aurélio Zezzi

DOI: 10.1007/978-3-319-90143-5

ISBN: 978-3-319-90142-8

Publisher: Springer International Publishing - Springer Journals

Jun 9, 2018

1 - 10 of 10 Chapters

LitStream

Chapter 1Metallomics: The Science of Biometals and Biometalloids

Maret, Wolfgang

Pages: 1 –20

[Metallomics, a discipline integrating sciences that address the biometals and biometalloids, provides new opportunities for discoveries. As part of a systems biology approach, it draws attention to the importance of many chemical elements in biochemistry. Traditionally, biochemistry has treated...
LitStream

Chapter 2Metallomics Applied to the Study of Neurodegenerative and Mental Diseases

Sussulini, Alessandra; Hauser-Davis, Rachel Ann

Pages: 21 –37

[Biochemical imbalances, provoked by aging or a secondary illness, might directly affect the brain, causing severe problems, such as loss of memory or alteration of behavior patterns. Brain disorders are usually classified as injuries (such as stroke, hematomas, and concussions), tumors, and...
LitStream

Chapter 3Environmental Metallomics

Rodríguez-Moro, Gema; Ramírez-Acosta, Sara; Arias-Borrego, Ana; García-Barrera, Tamara; Gómez-Ariza, José Luis

Pages: 39 –66

[Metallomics is the new paradigm about the metallobiomolecules related to living organisms, considering the interactions between toxic and essential metals, transport through biological fluids, passing across biological membranes and interfaces, synergic and antagonist actions among metal...
LitStream

Chapter 4Metallomics Study in Plants Exposed to Arsenic, Mercury, Selenium and Sulphur

Feldmann, Jörg; Bluemlein, Katharina; Krupp, Eva Maria; Mueller, Martin; Wood, Barry Alan

Pages: 67 –100

[This chapter is focussing on the interaction of arsenic, mercury and selenium with plans. Aspects of biotransformations are discussed, before the analytical methodologies are listed and critically appraised in the second part. A holistic view is given, starting from the soil environment and...
LitStream

Chapter 5Metallomics in Fish

Braga, Camila Pereira; Adamec, Jiri; de Magalhães Padilha, Pedro

Pages: 101 –110

[Metallomics allows the integration of traditionally analytical studies with inorganic and biochemical studies. The study of metallomics in living organisms allows us to obtain information about how the metal ion is distributed and coordinated with proteins, the essentiality and/or toxicity, and...
LitStream

Chapter 6The Use of Stable Isotopic Tracers in Metallomics Studies

Montes-Bayón, Maria; Bettmer, Jörg

Pages: 111 –137

[Mass spectrometry represents an essential technique in Metallomics studies. It permits the identification of metal-containing molecules as part of the metallome as well as their quantification at low concentration levels. The technique becomes even more powerful in combination with the use of...
LitStream

Chapter 7Bioimaging Metallomics

Dressler, Valderi Luiz; Müller, Edson Irineu; Pozebon, Dirce

Pages: 139 –181

[This chapter focuses on bioimaging in metallomics, which involves metal and metalloids distribution in animal tissues. It starts with laser ablation-inductively coupled plasma-mass spectrometry followed by secondary ion mass spectrometry, synchrotron-based X-ray fluorescence, and electron...
LitStream

Chapter 8Chemical Speciation and Metallomics

de Jesus, Jemmyson Romário; da Costa, Luana Ferreira; Lehmann, Eraldo Luiz; Galazzi, Rodrigo Moretto; Madrid, Katherine Chacón; Arruda, Marco Aurélio Zezzi

Pages: 183 –211

[Chemical speciation approaches is an inherent part of metallomics, once metals/metalloids and organic structures need to be currently evaluated for attaining metallomics studies. Then, this chapter focuses on the applications of the chemical speciation applied to the human health risk, food and...
LitStream

Chapter 9Advanced Nuclear and Related Techniques for Metallomics and Nanometallomics

Li, Yu-Feng; Zhao, Jiating; Gao, Yuxi; Chen, Chunying; Chai, Zhifang

Pages: 213 –243

[Metallomics, focusing on the global and systematic understanding of the metal uptake, trafficking, role, and excretion in biological systems, has attracted more and more attention. Metal-related nanomaterials, including metallic and metal-containing nanomaterials, have unique properties compared...
LitStream

Chapter 10New Frontiers of Metallomics: Elemental and Species-Specific Analysis and Imaging of Single Cells

Jiménez-Lamana, Javier; Szpunar, Joanna; Łobinski, Ryszard

Pages: 245 –270

[Single cells represent the basic building units of life, and thus their study is one the most important areas of research. However, classical analysis of biological cells eludes the investigation of cell-to-cell differences to obtain information about the intracellular distribution since it only...

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