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Hormones and the Brain

Part of the Research and Perspectives in Endocrine Interactions Book Series

Editors: Kordon, Claude; Gaillard, Rolf-Christian; Christen, Yves

DOI: 10.1007/b138340

ISBN: 978-3-540-21355-0

Publisher: Springer Berlin Heidelberg - Springer Journals

Jan 1, 2005

1 - 10 of 13 Chapters

LitStream

Chapter 1Activins and inhibins: Physiological roles, signaling mechanisms and regulation

Gray, Peter C.; Bilezikjian, Louise M.; Harrison, Craig A.; Wiater, Ezra; Vale, Wylie

Pages: 1 –28
LitStream

Chapter 2Twins and the fetal origins hypothesis: An application to growth data

Boomsma, Dorret; Willemsen, Gonneke; de Geus, Eco; Kupper, Nina; Posthuma, Danielle; IJzerman, Richard; Heijmans, Bas; Slagboom, Eline; Beeml, Leo; Dolan, Conor

Pages: 29 –46

[The Barker hypothesis states that size at birth is negatively associated with disease risk later in life. Numerous studies have tested and confirmed this hypothesis in singletons. Using twin (or sibling) data, several extensions of the Barker hypothesis may be considered: Within pairs, is the...
LitStream

Chapter 3Towards Understanding the Neurobiology of Mammalian Puberty: Genetic, Genomic and Proteomic Approaches

Ojeda, Sergio R.; Lomniczi, Alejandro; Mungenast, Alison; Mastronardi, Claudio; Parent, Anne-Simone; Roth, Christian; Prevot, Vincent; Hegeir, Sabine; Jung, Heike

Pages: 47 –60

[The pubertal activation of gonadotropin hormone-releasing hormone (GnRH) release in rodents and primates is brought about by coordinated changes in excitatory and inhibitory inputs to GnRH neurons. These inputs include both transsynaptic and glia-to-neuron communication pathways. Using cellular...
LitStream

Chapter 4The non-genomic Action of Sex Steroids

Joe, I; Kipp, J L; Ramirez, V D

Pages: 61 –72

[The aim of this paper is to discuss novel and rather recent evidence indicating that estradiol and testosterone have rapid actions by interacting with two different, but physiologically and chemically well-characterized proteins: 1) tubulin, a basic component of microtubules and therefore...
LitStream

Chapter 5Mechanisms of Steroid Hormone Actions on Hypothalamic Nerve Cells: Molecular and Biophysical Studies relevant for Hormone-dependent Behaviors

Kow, Lee-Ming; Vasudevan, Nandini; Devidze, Nino; Ragnauth, Andre; Pfaff, Donald W.

Pages: 73 –77

[Genes turned on by hormones and genes whose products are essential for hormone-controlled behaviors have received intense study during the last 20 years. Now, we see that steroid hormones can also affect nerve cells by rapid membrane actions in addition to slower genomic actions. At the...
LitStream

Chapter 6Biological Effects and Markers of Exposure to Xenosteroids and Selective Estrogen Receptor Modulators (SERMs) at the Hypothalamic-Pituitary Unit

Tena-Sempere, M.; Aguilarl, E.

Pages: 79 –98

[Estrogen is a pivotal factor in the regulation of a wide array of biological systems, in both the male and the female, which include not only the reproductive axis but also bone, the cardiovascular system, adipose tissue and the brain. In recent years, the biological effects and mechanisms of...
LitStream

Chapter 7Regulation of Neurosteroid Biosynthesis by Neurotransmitters and Neuropeptides

Vaudry, H.; Do Rego, J.L.; Beaujean-Burel, D.; Leprince, J.; Galas, L.; Larhammar, D.; Fredriksson, R.; Luu-The, V.; Pelletier, G.; Tonon, M.C.; Delarue, C.

Pages: 99 –109

[It is now established that the brain has the capability of synthesizing biologically active steroids, termed neurosteroids, that participate in the regulation of various neurophysiological and behavioral processes. However, the neuronal mechanisms regulating the activity of...
LitStream

Chapter 8Progestins and antiprogestins: mechanisms of action, neuroprotection and myelination

Schumacher, M.; Ghoumari, A.; Guennoun, R.; Labombarda, F.; Gonzalez, S.L.; Gonzalez Deniselle, M.C.; Massaad, C.; Grenier, J.; Rajkowski, K.M.; Robert, F.; Baulieu, E.E.; De Nicola, A.F.

Pages: 111 –154

[Progesterone, originally considered as a hormone involved only in reproductive functions, exerts pleiotropic effects throughout the central and peripheral nervous systems. As early as 10 years ago, its role in myelination had been demonstrated in the regenerating peripheral nerve and in...
LitStream

Chapter 9Rapid Effects of Estradiol on Motivated Behaviors

Becker, Jill B.

Pages: 155 –172

[Estradiol can act extracellularly to rapidly enhance dopamine (DA) activity in striatum and nucleus accumbens (NAcc) as well as the behavioral response to psychomotor stimulants. Considerable research has demonstrated that the effects of estradiol on behavioral and neurochemical indices of DA...
LitStream

Chapter 10Behavioral Effects of rapid Changes in Aromatase Activity in the Central Nervous System

Balthazart, J.; Baillien, M.; Cornil, C.A.; Charlier, T.D.; Evrard, H.C.; Ball, G.F.

Pages: 173 –199

[In many vertebrate species, male sexual behavior is activated by the action in the preoptic area of estrogens produced by the local aromatization of testosterone. Estrogens bind to intracellular receptors, which then act as transcription factors to activate the behavior. In parallel, changes in...

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