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Immunological Investigations

Subject Areas: Immunology
Publisher: Taylor & Francis - Taylor & Francis
ISSN: 0882-0139
SJR: 50

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Journal Article

Insights into the Roles of Natural Killer Cells in Osteoarthritis

Zheng, Chang-Qing; Zeng, Ling-Jun; Liu, Zhi-Hong; Miao, Chen-Fang; Yao, Ling-Yan; Song, Hong-Tao; Hu, Xiao-Mu; Zhou, Xin

2024 Immunological Investigations

doi:10.1080/08820139.2024.2337025 pmid:38622991

Osteoarthritis (OA) is now widely acknowledged as a low-grade inflammatory condition, in which the intrinsic immune system plays a significant role in its pathogenesis. While the involvement of macrophages and T cells in the development of OA has been extensively reviewed, recent research has...
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Journal Article

Mannose Binding Lectin and C3 Serum Levels in Coronary Artery Disease: A Cross-Sectional Study

Meneghetti da Rosa, Juliana; Lidani, Kárita Cláudia Freitas; Andrade, Fabiana Antunes; Sena, Léia; Nisihara, Renato; Ambrosio, Altair Rogerio; Messias-Reason, Iara J.

2024 Immunological Investigations

doi:10.1080/08820139.2024.2337023

Background The process of tissue injury in coronary artery disease (CAD) has been associated with activation of the complement system, partly due to the action of mannose-binding lectin (MBL) and C3, which are expressed in atherosclerotic lesions. Objective The aim of this study was to evaluate...
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Journal Article

Upregulation, Functional Association, and Correlated Expressions of TRPV1 and TRPA1 During Telmisartan-Driven Immunosuppression of T Cells

Mukherjee, Tathagata; Tung, Kshyama Subhadarsini; Jena, Parthasarathi; Goswami, Chandan; Chattopadhyay, Subhasis

2024 Immunological Investigations

doi:10.1080/08820139.2024.2329203 pmid:38584464

TRPV1 and TRPA1, are known to be functionally expressed in T cells, where these two channels differentially regulate effector immune responses. Telmisartan (TM), an anti-hypertension drug, has been recently repurposed to suppress various inflammatory responses. However, the possible involvement...
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Journal Article

GBM Immunotherapy: Macrophage Impacts

Loginova, Nina; Aniskin, Denis; Timashev, Peter; Ulasov, Ilya; Kharwar, Rajesh Kumar

2024 Immunological Investigations

doi:10.1080/08820139.2024.2337022

Background Glioblastoma (GBM) is an extremely aggressive form of brain tumor with low survival rates. Current treatments such as chemotherapy, radiation, and surgery are problematic due to tumor growth, invasion, and tumor microenvironment. GBM cells are resistant to these standard treatments,...

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