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Analytical Chemistry Insights Volume 5: March

Subject Areas: Biochemistry
Publisher: SAGE PublicationsSage UK: London, England - SAGE
ISSN: 1177-3901
SJR: 19

LitStream

Journal Article

A Modified Method for Determination of Lumefantrine in Human Plasma by HPLC-UV and Combination of Protein Precipitation and Solid-Phase Extraction: Application to a Pharmacokinetic Study:

Huang, Liusheng; Lizak, Patricia S.; Jayewardene, Anura L.; Marzan, Florence; Lee, Ming-Na Tina; Aweeka, Francesca T

2010 Analytical Chemistry Insights

doi:10.4137/aci.s4431 pmid:20448843

An HPLC-UV method was developed and validated for the determination of lumefantrine in human plasma. Lumefantrine and its internal standard halofantrine were extracted from plasma samples using protein precipitation with acetonitrile (0.2% perchloric acid) followed by solid-phase extraction with...

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