Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

Journal Article

Class IC Antiarrhythmic Drugs: Informed Choice

Sydorova, Nataliia

2023 Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

doi:10.2478/prolas-2023-0012

AbstractThe article presents data on the most commonly used antiarrhythmic drugs of subclass IC: propafenone, flecainide, and a drug manufactured in Latvia — ethacizine. The features and priority areas of each drug use were identified. The author conducted a critical analysis of the results of...

Open Access

Journal Article

Impact of the COVID-19 Pandemic on the Mortality Rate and Clinical Outcome of Patients Admitted to Pauls Stradiņš Clinical University Hospital With Spontaneous Intracerebral Haemorrhage

Blimhena-Pastare, Inese; Valante, Ramona; Teivāne, Agnete; Miglāne, Evija

2023 Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

doi:10.2478/prolas-2023-0013

AbstractSpontaneous intracerebral haemorrhage (SICH) remains the most devastating type of stroke with the highest morbidity and mortality. Since the start of the COVID-19 pandemic, serious modifications have been made in health care systems, affecting patients with all kinds of disease, including...

Open Access

Journal Article

Antimutagenic 1,4-Dihydropyridine AV-153 Normalizes Expression of GLUT1, GLUT4, INOS, PARP1, and Gamma H2AX Histone in Myocardium of Rats with Streptozotocin Model of Diabetes Mellitus

Rostoka, Evita; Isajevs, Sergejs; Sokolovska, Jeļizaveta; Duburs, Gunārs; Sjakste, Nikolajs

2023 Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

doi:10.2478/prolas-2023-0014

AbstractDiabetic cardiomyopathy increases the risk of heart failure and worsens prognosis for diabetes mellitus (DM) patients. Its development depends on many factors, including modification of nitric oxide production and impaired DNA repair. The goal of the present work was to study in vivo...

Open Access

Journal Article

Evaluation of the Impact of Nutrition Knowledge on Nutrition Behaviour and Diet in a Physically Active Person’s Cohort

Plaviņa, Liāna; Umbraško, Silvija; Asare, Lāsma; Edelmers, Edgars

2023 Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

doi:10.2478/prolas-2023-0015

AbstractSpecific high physical and psychological load energy expenditure should be covered by balanced diet that is adapted to physical load. Food intake is one of the vital processes that support body activity and maintain physical working capacity in special environment. Various objective and...

Open Access

Journal Article

A Matlab-Based Approach for Estimating the Area Taken Up by Cells Attached to Micropatterned Optically Opaque Surfaces

Dekhtyar, Yuri; Sorokins, Hermanis; Teifurova, Sabīne

2023 Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

doi:10.2478/prolas-2023-0016

AbstractCell attachment is of paramount importance in implant design, bioreactor design, tissue engineering and the design of non-fouling surfaces. Surface roughness is a significant factor that affects cell attachment. To explore the impact of roughness characteristics, micromachining approaches...

Open Access

Journal Article

Histological Characteristics of the Endometrium and its Affecting Factors in Dairy Cattle (Bos taurus) on Embryo Transfer Day

Pigiņka-Vjačeslavova, Inga; Ponomarjova, Olga; Lacberga, Lāsma; Šematoviča, Ilga; Zolovs, Maksims;

2023 Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

doi:10.2478/prolas-2023-0017

AbstractIn cows embryo transfer occurs on the 7th day of the oestrous cycle. Embryo survival and successful pregnancy depend on many factors, including early interaction between embryo and endometrium. Therefore, the aim of our research was to describe histo-morphological characteristics of...

Open Access

Journal Article

Quantitative Assessment of Indispensable Amino Acids in the Flour Confectionery Food Products of Plant Origin — Tofu Cake and Tofu Muffin with Chickpea Flour

Jansone, Liene; Kunkulberga, Daiga

2023 Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

doi:10.2478/prolas-2023-0018

AbstractThe article provides a study of the quantitative composition of amino acids in some baked flour confectionery product of plant and animal origin. The objective of the study was to determine the profiles of indispensable amino acids in several products. Source materials with high content...

Open Access

Journal Article

A Sensory Evaluation of Arabica Gayo Coffee Flavour Based on Varieties and Processing Techniques

Fadhil, Rahmat; Nurba, Diswandi; Fachruddin, Fachruddin

2023 Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

doi:10.2478/prolas-2023-0019

AbstractPost-harvest handling of coffee is one of the main factors in producing a high-quality coffee, including its processing techniques. This study aimed to conduct a sensory evaluation of arabica Gayo coffee flavour in various varieties and processing techniques. There were four selected...

Open Access

Journal Article

Penetrance of CHEK2 and BRCA1 Double Heterozygotes in Breast and/or Ovarian Cancer Patients

Berga-Švītiņa, Egija; Pirsko, Valdis; Nakazawa-Miklaševiča, Miki; Maksimenko, Jeļena; Gardovskis, Jānis;

2023 Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences

doi:10.2478/prolas-2023-0020

AbstractGermline pathogenic BRCA1 variants confer increased risk of breast and/or ovarian cancer. The penetrance of BRCA1 pathogenic variants is variable due to the effects of other genetic factors. The interaction between CHEK2 and BRCA1 proteins is crucial in homology directed DNA repair...

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