Access the full text.
Sign up today, get DeepDyve free for 14 days.
Jason Buenrostro, P. Giresi, Lisa Zaba, Howard Chang, W. Greenleaf (2013)
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome positionNature Methods, 10
Lei Sun, L. Goff, C. Trapnell, Ryan Alexander, Kinyui Lo, Ezgi Hacisuleyman, Martin Sauvageau, B. Tazón-Vega, David Kelley, David Hendrickson, Bingbing Yuan, Manolis Kellis, H. Lodish, J. Rinn (2013)
Long noncoding RNAs regulate adipogenesisProceedings of the National Academy of Sciences, 110
E. Eklund (2006)
The role of HOX genes in myeloid leukemogenesisCurrent Opinion in Hematology, 13
I. Ulitsky, D. Bartel (2013)
lincRNAs: Genomics, Evolution, and MechanismsCell, 154
M. Guttman, P. Russell, Nicholas Ingolia, J. Weissman, E. Lander (2013)
Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode ProteinsCell, 154
J. Alvarez-Dominguez, Wenqian Hu, Bingbing Yuan, Jiahai Shi, Staphany Park, Austin Gromatzky, A. Oudenaarden, H. Lodish (2014)
Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation.Blood, 123 4
ENCODEConsortium, Martin Min (2012)
An Integrated Encyclopedia of DNA Elements in the Human GenomeNature, 489
E. Kim, Adam Wespiser, Daniel Caffrey (2016)
The domain structure and distribution of Alu elements in long noncoding RNAs and mRNAsRNA, 22
Kojiro Sato, F. Miyoshi, K. Yokota, Y. Araki, Y. Asanuma, Y. Akiyama, K. Yoh, Satoru Takahashi, H. Aburatani, T. Mimura (2011)
Marked Induction of c-Maf Protein during Th17 Cell Differentiation and Its Implication in Memory Th Cell Development*The Journal of Biological Chemistry, 286
P. Linder, E. Jankowsky (2011)
From unwinding to clamping — the DEAD box RNA helicase familyNature Reviews Molecular Cell Biology, 12
(2013)
High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation
K. Rice, J. Licht (2007)
HOX deregulation in acute myeloid leukemia.The Journal of clinical investigation, 117 4
D. Görlich, U. Kutay (1999)
Transport between the cell nucleus and the cytoplasm.Annual review of cell and developmental biology, 15
G. Pageau, L. Hall, S. Ganesan, D. Livingston, J. Lawrence (2007)
The disappearing Barr body in breast and ovarian cancersNature Reviews Cancer, 7
N. Niitsu, K. Sasaki, M. Umeda (1999)
A high serum soluble Fas/APO-1 level is associated with a poor outcome of aggressive non-Hodgkin’s lymphomaLeukemia, 13
Alice Liu, B. Torchia, B. Migeon, Robert Siliciano (1997)
The human NTT gene: identification of a novel 17-kb noncoding nuclear RNA expressed in activated CD4+ T cells.Genomics, 39 2
R. Wiberg, R. Wiberg, D. Halligan, R. Ness, A. Necsulea, Henrik Kaessmann, P. Keightley (2015)
Assessing Recent Selection and Functionality at Long Noncoding RNA Loci in the Mouse GenomeGenome Biology and Evolution, 7
M. Tayari, Melanie Winkle, Gertrud Kortman, Jantine Sietzema, D. Jong, M. Terpstra, Pieter Mestdagh, Frans Kroese, L. Visser, A. Diepstra, K. Kok, A. Berg, J. Kluiver (2016)
Long Noncoding RNA Expression Profiling in Normal B-Cell Subsets and Hodgkin Lymphoma Reveals Hodgkin and Reed-Sternberg Cell-Specific Long Noncoding RNAs.The American journal of pathology, 186 9
Nicholas IIott, J. Heward, B. Roux, E. Tsitsiou, P. Fenwick, L. Lenzi, I. Goodhead, C. Hertz-Fowler, A. Heger, N. Hall, L. Donnelly, D. Sims, M. Lindsay (2014)
Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytesNature Communications, 5
Je-Hyun Yoon, K. Abdelmohsen, S. Srikantan, Xiaoling Yang, J. Martindale, Supriyo De, Maite Huarte, Ming Zhan, K. Becker, M. Gorospe (2012)
LincRNA-p21 suppresses target mRNA translation.Molecular cell, 47 4
M. Muramatsu, K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, T. Honjo (2000)
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing EnzymeCell, 102
Sonia Sharma, Gregory Findlay, Hozefa Bandukwala, Shalini Oberdoerffer, Beate Baust, Zhigang Li, V. Schmidt, P. Hogan, D. Sacks, A. Rao (2011)
Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complexProceedings of the National Academy of Sciences, 108
Evangelos Pefanis, Jiguang Wang, Gerson Rothschild, Junghyun Lim, David Kazadi, Jianbo Sun, Alexander Federation, Jaime Chao, Oliver Elliott, Zhiping Liu, A. Economides, J. Bradner, R. Rabadán, Uttiya Basu (2015)
RNA Exosome-Regulated Long Non-Coding RNA Transcription Controls Super-Enhancer ActivityCell, 161
Zhonghan Li, T. Chao, Kung-yen Chang, Nianwei Lin, Veena Patil, C. Shimizu, S. Head, J. Burns, T. Rana (2013)
The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPLProceedings of the National Academy of Sciences, 111
J. Engreitz, Amy Pandya-Jones, P. McDonel, Alexander Shishkin, Klára Sirokmán, Christine Surka, Sabah Kadri, Jeff Xing, A. Goren, E. Lander, K. Plath, M. Guttman (2013)
The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X ChromosomeScience, 341
Jiyoti Verma-Gaur, A. Torkamani, L. Schaffer, S. Head, N. Schork, A. Feeney (2012)
Noncoding transcription within the Igh distal VH region at PAIR elements affects the 3D structure of the Igh locus in pro-B cellsProceedings of the National Academy of Sciences, 109
J. Engreitz, Klára Sirokmán, P. McDonel, Alexander Shishkin, Christine Surka, P. Russell, S. Grossman, A. Chow, M. Guttman, E. Lander (2014)
RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin SitesCell, 159
A. Miele, J. Dekker (2009)
Mapping cis- and trans- chromatin interaction networks using chromosome conformation capture (3C).Methods in molecular biology, 464
I. Ivanov, Brent McKenzie, Liang Zhou, C. Tadokoro, A. Lepelley, J. Lafaille, D. Cua, D. Littman (2006)
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.Cell, 126 6
C. Clemson, John Hutchinson, S. Sara, A. Ensminger, A. Fox, A. Chess, J. Lawrence (2009)
An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles.Molecular cell, 33 6
S. Vigneau, P. Rohrlich, M. Brahic, J. Bureau (2003)
Tmevpg1, a Candidate Gene for the Control of Theiler's Virus Persistence, Could Be Implicated in the Regulation of Gamma InterferonJournal of Virology, 77
Jonathan Kotzin, Sean Spencer, S. McCright, Dinesh Kumar, Magalie Collet, Walter Mowel, Ellen Elliott, A. Uyar, M. Makiya, Margaret Dunagin, Christian Harman, Anthony Virtue, Stella Zhu, Will Bailis, Judith Stein, C. Hughes, A. Raj, E. Wherry, L. Goff, A. Klion, J. Rinn, Adam Williams, R. Flavell, Jorge Henao-Mejia (2016)
The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespanNature, 537
(2015)
The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4
Qiang Tong, A. Gong, Xin‐Tian Zhang, Chengchi Lin, Shibin Ma, Jing Chen, Guoku Hu, Xian-Ming Chen (2016)
LincRNA‐Cox2 modulates TNF‐α‐induced transcription of Il12b gene in intestinal epithelial cells through regulation of Mi‐2/NuRD‐mediated epigenetic histone modificationsThe FASEB Journal, 30
Sheena Saayman, Amanda Ackley, Anne-Marie Turner, M. Famiglietti, A. Bosque, Matthew Clemson, V. Planelles, K. Morris (2014)
An HIV-Encoded Antisense Long Noncoding RNA Epigenetically Regulates Viral Transcription.Molecular therapy : the journal of the American Society of Gene Therapy, 22 6
David Kelley, J. Rinn (2012)
Transposable elements reveal a stem cell-specific class of long noncoding RNAsGenome Biology, 13
E. Yildirim, J. Kirby, Diane Brown, F. Mercier, R. Sadreyev, D. Scadden, Jeannie Lee (2013)
Xist RNA Is a Potent Suppressor of Hematologic Cancer in MiceCell, 152
J. Rinn, Howard Chang (2012)
Genome regulation by long noncoding RNAs.Annual review of biochemistry, 81
Jennie Chan, Maninjay Atianand, Zhaozhao Jiang, Susan Carpenter, D. Aiello, R. Elling, K. Fitzgerald, Daniel Caffrey (2015)
Cutting Edge: A Natural Antisense Transcript, AS-IL1α, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1αThe Journal of Immunology, 195
Xueqing Zhang, Z. Lian, C. Padden, M. Gerstein, J. Rozowsky, Michael Snyder, T. Gingeras, P. Kapranov, S. Weissman, P. Newburger (2009)
A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster.Blood, 113 11
Ci Chu, K. Qu, F. Zhong, S. Artandi, Howard Chang (2011)
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions.Molecular cell, 44 4
Nicole Rapicavoli, K. Qu, Jiajing Zhang, Megan Mikhail, Rémi-Martin Laberge, Howard Chang (2013)
A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeuticseLife, 2
Allison Martin, Yong Li (2007)
RNase MRP RNA and human genetic diseasesCell Research, 17
D. Patel, V. Kuchroo (2015)
Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions.Immunity, 43 6
Wenqian Hu, Bingbing Yuan, J. Flygare, H. Lodish (2011)
Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation.Genes & development, 25 24
L. Bei, Yufeng Lu, S. Bellis, W. Zhou, E. Horvath, E. Eklund (2007)
Identification of a HoxA10 Activation Domain Necessary for Transcription of the Gene Encoding β3 Integrin during Myeloid Differentiation*Journal of Biological Chemistry, 282
H. Medyouf, Samuel Gusscott, Hongfang Wang, Jen-Chieh Tseng, C. Wai, Oksana Nemirovsky, A. Trumpp, F. Pflumio, J. Carboni, M. Gottardis, M. Pollak, A. Kung, J. Aster, M. Holzenberger, A. Weng (2011)
High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signalingThe Journal of Experimental Medicine, 208
Alicia Schep, Jason Buenrostro, Sarah Denny, Katja Schwartz, G. Sherlock, W. Greenleaf (2015)
Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regionsGenome Research, 25
A. Castellanos-Rubio, N. Fernández-Jiménez, R. Kratchmarov, Xiaobing Luo, G. Bhagat, P. Green, R. Schneider, M. Kiledjian, J. Bilbao, S. Ghosh (2016)
A long noncoding RNA associated with susceptibility to celiac diseaseScience, 352
T. Brazão, Jethro Johnson, Jennifer Müller, A. Heger, C. Ponting, V. Tybulewicz (2016)
Long noncoding RNAs in B-cell development and activation.Blood, 128 7
Ci Chu, Ci Chu, Q. Zhang, S. Rocha, Ryan Flynn, Maheetha Bharadwaj, J. Calabrese, T. Magnuson, E. Heard, Howard Chang (2015)
Systematic Discovery of Xist RNA Binding ProteinsCell, 161
Phillip Grote, L. Wittler, D. Hendrix, Frederic Koch, Sandra Währisch, Arica Beisaw, Karol Macura, Gaby Bläss, Manolis Kellis, Martin Werber, B. Herrmann (2013)
The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.Developmental cell, 24 2
M. Guttman, Julie Donaghey, B. Carey, M. Garber, Jennifer Grenier, Glen Munson, Geneva Young, Anne Lucas, Robert Ach, Laurakay Bruhn, Xiaoping Yang, Ido Amit, Alexander Meissner, Aviv Regev, J. Rinn, David Root, Eric Lander (2011)
lincRNAs act in the circuitry controlling pluripotency and differentiationNature, 477
Michael Lin, Irwin Jungreis, Manolis Kellis (2011)
PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regionsBioinformatics, 27
Guoku Hu, A. Gong, Yang Wang, Shibin Ma, Xiqiang Chen, Jing Chen, C. Su, A. Shibata, J. Strauss-Soukup, K. Drescher, Xian-Ming Chen (2016)
LincRNA-Cox2 Promotes Late Inflammatory Gene Transcription in Macrophages through Modulating SWI/SNF-Mediated Chromatin RemodelingThe Journal of Immunology, 196
Pin Wang, Yiquan Xue, Yanmei Han, Li Lin, Cong Wu, Sheng Xu, Zhengping Jiang, Junfang Xu, Qiuyan Liu, Xuetao Cao (2014)
The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell DifferentiationScience, 344
Arnav Mehta, D. Baltimore (2016)
MicroRNAs as regulatory elements in immune system logicNature Reviews Immunology, 16
T. Murphy, G. Grajales-Reyes, Xiaodi Wu, R. Tussiwand, Carlos Briseño, A. Iwata, Nicole Kretzer, V. Durai, K. Murphy (2016)
Transcriptional Control of Dendritic Cell Development.Annual review of immunology, 34
R. Bonnal, V. Ranzani, Alberto Arrigoni, S. Curti, I. Panzeri, P. Gruarin, S. Abrignani, G. Rossetti, M. Pagani (2015)
De novo transcriptome profiling of highly purified human lymphocytes primary cellsScientific Data, 2
Ouyang Jing, Xiaomei Zhu, Yuhai Chen, Haitao Wei, Qinghuang Chen, Xiaojuan Chi, Baomin Qi, Lianfeng Zhang, Yi Zhao, G. Gao, Guoshun Wang, Jilong Chen (2014)
NRAV, a Long Noncoding RNA, Modulates Antiviral Responses through Suppression of Interferon-Stimulated Gene TranscriptionCell Host & Microbe, 16
W. Huang, B. Thomas, Ryan Flynn, Samuel Gavzy, Lin Wu, Sangwon Kim, J. Hall, Emily Miraldi, Charles Ng, F. Rigo, Sarah Meadows, Nina Montoya, Natalia Herrera, A. Domingos, F. Rastinejad, R. Myers, F. Fuller-Pace, Richard Bonneau, Howard Chang, O. Acuto, D. Littman (2015)
DDX5 and its associated lncRNA Rmrp modulate Th17 cell effector functionsNature, 528
Thomas Trimarchi, E. Bilal, P. Ntziachristos, G. Fabbri, R. Dalla-Favera, A. Tsirigos, I. Aifantis (2014)
Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute LeukemiaCell, 158
I. Ricaño-Ponce, C. Wijmenga (2013)
Mapping of immune-mediated disease genes.Annual review of genomics and human genetics, 14
Miao-Chih Tsai, Ohad Manor, Y. Wan, N. Mosammaparast, Jordon Wang, F. Lan, Yang Shi, E. Segal, Howard Chang (2010)
Long Noncoding RNA as Modular Scaffold of Histone Modification ComplexesScience, 329
Kate Broadbent, Daniel Park, A. Wolf, D. Tyne, Jennifer Sims, U. Ribacke, S. Volkman, M. Duraisingh, D. Wirth, Pardis Sabeti, J. Rinn (2011)
A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAsGenome Biology, 12
Maninjay Atianand, Wenqian Hu, Ansuman Satpathy, Ying Shen, Emiliano Ricci, J. Alvarez-Dominguez, Ankit Bhatta, Stefan Schattgen, Jason McGowan, Juliana Blin, Joerg Braun, Pallavi Gandhi, M. Moore, Howard Chang, H. Lodish, Daniel Caffrey, K. Fitzgerald (2016)
A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain InflammationCell, 165
M. Krawczyk, B. Emerson (2014)
p50-associated COX-2 extragenic RNA (PACER) activates COX-2 gene expression by occluding repressive NF-κB complexeseLife, 3
Sarah Collier, P. Collins, C. Williams, M. Boothby, T. Aune (2012)
Cutting Edge: Influence of Tmevpg1, a Long Intergenic Noncoding RNA, on the Expression of Ifng by Th1 CellsThe Journal of Immunology, 189
L. Sehgal, R. Mathur, F. Braun, J. Wise, Z. Berková, S. Neelapu, L. Kwak, F. Samaniego (2014)
FAS-antisense 1 lncRNA and production of soluble versus membrane Fas in B-cell lymphomaLeukemia, 28
D. Bolland, Andrew Wood, Colette Johnston, S. Bunting, G. Morgan, L. Chakalova, P. Fraser, A. Corcoran (2004)
Antisense intergenic transcription in V(D)J recombinationNature Immunology, 5
A. Necsulea, M. Soumillon, Maria Warnefors, A. Liechti, Tasman Daish, U. Zeller, J. Baker, F. Grützner, H. Kaessmann (2014)
The evolution of lncRNA repertoires and expression patterns in tetrapodsNature, 505
Wenqian Hu, J. Alvarez-Dominguez, H. Lodish (2012)
Regulation of mammalian cell differentiation by long non‐coding RNAsEMBO reports, 13
V. Scaria, Ayesha Pasha (2013)
Long Non-Coding RNAs in Infection BiologyFrontiers in Genetics, 3
S. Schmidt, Andrea Niño-Castro, J. Schultze (2012)
Regulatory dendritic cells: there is more than just immune activationFrontiers in Immunology, 3
T. Hirose, Giorgio Virnicchi, Akie Tanigawa, T. Naganuma, Ruohan Li, H. Kimura, Takahide Yokoi, S. Nakagawa, M. Benard, A. Fox, G. Pierron (2014)
NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodiesMolecular Biology of the Cell, 25
C. Carrieri, L. Cimatti, M. Biagioli, Anne Beugnet, S. Zucchelli, Stefania Fedele, E. Pesce, I. Ferrer, Licio Collavin, C. Santoro, A. Forrest, Piero Carninci, S. Biffo, E. Stupka, S. Gustincich (2012)
Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeatNature, 491
Shan Sun, B. Rosario, A. Szántó, Y. Ogawa, Yesu Jeon, Jeannie Lee (2013)
Jpx RNA Activates Xist by Evicting CTCFCell, 153
M. Dinger, K. Pang, T. Mercer, J. Mattick (2008)
Differentiating Protein-Coding and Noncoding RNA: Challenges and AmbiguitiesPLoS Computational Biology, 4
R. Medzhitov, T. Horng (2009)
Transcriptional control of the inflammatory responseNature Reviews Immunology, 9
Stefan Washietl, Manolis Kellis, Manuel Garber (2014)
Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammalsGenome Research, 24
A. Kapusta, Zev Kronenberg, Vincent Lynch, Xiaoyu Zhuo, L. Ramsay, G. Bourque, M. Yandell, C. Feschotte (2013)
Transposable Elements Are Major Contributors to the Origin, Diversification, and Regulation of Vertebrate Long Noncoding RNAsPLoS Genetics, 9
J. Gomez, Orly Wapinski, Yul Yang, J. Bureau, Smita Gopinath, D. Monack, Howard Chang, M. Brahic, K. Kirkegaard (2013)
The NeST Long ncRNA Controls Microbial Susceptibility and Epigenetic Activation of the Interferon-γ LocusCell, 152
J. Dijkstra, K. Ballingall (2014)
Non-human lnc-DC orthologs encode Wdnm1-like proteinF1000Research, 3
Caryn Wadler, Carin Vanderpool (2007)
A dual function for a bacterial small RNA: SgrS performs base pairing-dependent regulation and encodes a functional polypeptideProceedings of the National Academy of Sciences, 104
M. Simon, Charlotte Wang, P. Kharchenko, J. West, B. Chapman, A. Alekseyenko, M. Borowsky, M. Kuroda, R. Kingston (2011)
The genomic binding sites of a noncoding RNAProceedings of the National Academy of Sciences, 108
J. Harrow, A. Frankish, J. Gonzalez, Electra Tapanari, M. Diekhans, F. Kokocinski, Bronwen Aken, D. Barrell, A. Zadissa, S. Searle, If Barnes, A. Bignell, Veronika Boychenko, T. Hunt, M. Kay, Gaurab Mukherjee, J. Rajan, Gloria Despacio-Reyes, Gary Saunders, C. Steward, R. Harte, Michael Lin, C. Howald, Andrea Tanzer, T. Derrien, Jacqueline Chrast, Nathalie Walters, S. Balasubramanian, Baikang Pei, M. Tress, J. Rodríguez, Iakes Ezkurdia, Jeltje Baren, M. Brent, D. Haussler, Manolis Kellis, A. Valencia, A. Reymond, M. Gerstein, R. Guigó, T. Hubbard (2012)
GENCODE: The reference human genome annotation for The ENCODE ProjectGenome Research, 22
Lei Kong, Yong Zhang, Zhi-Qiang Ye, Xiao-Qiao Liu, Shuqi Zhao, Liping Wei, Ge Gao (2007)
CPC: assess the protein-coding potential of transcripts using sequence features and support vector machineNucleic Acids Research, 35
Rajnish Gupta, Nilay Shah, Kevin Wang, Jeewon Kim, H. Horlings, D. Wong, Miao-Chih Tsai, T. Hung, P. Argani, J. Rinn, Yulei Wang, P. Brzoska, Benjamin Kong, Rui Li, R. West, M. Vijver, S. Sukumar, Howard Chang (2010)
Long noncoding RNA HOTAIR reprograms chromatin state to promote cancer metastasisNature, 464
D. Cazalla, Joan Steitz (2010)
Down-regulation of a host microRNA by a viral noncoding RNA.Cold Spring Harbor symposia on quantitative biology, 75
M. Kretz, Z. Siprashvili, Ci Chu, Dan Webster, Ashley Zehnder, K. Qu, Carolyn Lee, Ross Flockhart, A. Groff, Jennifer Chow, Danielle Johnston, Grace Kim, R. Spitale, Ryan Flynn, Grace Zheng, Subhadra Aiyer, A. Raj, J. Rinn, Howard Chang, P. Khavari (2012)
Control of somatic tissue differentiation by the long non-coding RNA TINCRNature, 493
Vinod Kumar, H. Westra, J. Karjalainen, D. Zhernakova, T. Esko, B. Hrdličková, Rodrigo Almeida, A. Zhernakova, E. Reinmaa, U. Võsa, M. Hofker, R. Fehrmann, Jingyuan Fu, S. Withoff, A. Metspalu, L. Franke, C. Wijmenga (2013)
Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA ExpressionPLoS Genetics, 9
I. Ho, D. Lo, L. Glimcher (1998)
c-maf Promotes T Helper Cell Type 2 (Th2) and Attenuates Th1 Differentiation by Both Interleukin 4–dependent and –independent MechanismsThe Journal of Experimental Medicine, 188
T. Morita, H. Aiba (2007)
Small RNAs making a small proteinProceedings of the National Academy of Sciences, 104
A. Willingham, A. Orth, S. Batalov, E. Peters, B. Wen, P. Aza‐Blanc, J. Hogenesch, Peter Schultz, P. Schultz (2005)
A Strategy for Probing the Function of Noncoding RNAs Finds a Repressor of NFATScience, 309
T. Derrien, Rory Johnson, G. Bussotti, Andrea Tanzer, S. Djebali, Hagen Tilgner, G. Guernec, David Martin, A. Merkel, David Knowles, Julien Lagarde, Lavanya Veeravalli, Xiaoan Ruan, Y. Ruan, T. Lassmann, Piero Carninci, James Brown, L. Lipovich, J. Gonzalez, Mark Thomas, Carrie Davis, R. Shiekhattar, T. Gingeras, T. Hubbard, Cédric Notredame, J. Harrow, R. Guigó (2012)
The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expressionGenome Research, 22
T. Korn, E. Bettelli, M. Oukka, V. Kuchroo (2009)
IL-17 and Th17 Cells.Annual review of immunology, 27
A. Werner, Mark Carlile, D. Swan (2009)
What do natural antisense transcripts regulate?RNA Biology, 6
D. Gallie (2015)
Faculty Opinions recommendation of The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.
Xinxia Peng, Lisa Gralinski, C. Armour, M. Ferris, Matthew Thomas, S. Proll, B. Bradel-Tretheway, M. Korth, J. Castle, M. Biery, H. Bouzek, D. Haynor, M. Frieman, M. Heise, C. Raymond, R. Baric, M. Katze (2010)
Unique Signatures of Long Noncoding RNA Expression in Response to Virus Infection and Altered Innate Immune SignalingmBio, 1
S. Nakayamada, Hayato Takahashi, Y. Kanno, J. O’Shea (2012)
Helper T cell diversity and plasticity.Current opinion in immunology, 24 3
S. Hedges (2002)
The origin and evolution of model organismsNature Reviews Genetics, 3
R. Steinman, H. Hemmi (2006)
Dendritic cells: translating innate to adaptive immunity.Current topics in microbiology and immunology, 311
M. Cesana, D. Cacchiarelli, I. Legnini, Tiziana Santini, O. Sthandier, M. Chinappi, A. Tramontano, I. Bozzoni (2011)
A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNACell, 147
Bodu Liu, Lijuan Sun, Qiang Liu, C. Gong, Yandan Yao, Xiaobin Lv, Ling Lin, H. Yao, F. Su, Dangsheng Li, M. Zeng, E. Song (2015)
A cytoplasmic NF-κB interacting long noncoding RNA blocks IκB phosphorylation and suppresses breast cancer metastasis.Cancer cell, 27 3
C. Rudin, C. Thompson (1997)
Apoptosis and disease: regulation and clinical relevance of programmed cell death.Annual review of medicine, 48
Quan Zhang, Chia-yen Chen, V. Yedavalli, K. Jeang (2013)
NEAT1 Long Noncoding RNA and Paraspeckle Bodies Modulate HIV-1 Posttranscriptional ExpressionmBio, 4
The discovery of long noncoding RNAs (lncRNA) has provided a new perspective on gene regulation in diverse biological contexts. lncRNAs are remarkably versatile molecules that interact with RNA, DNA, or proteins to promote or restrain the expression of protein-coding genes. Activation of immune cells is associated with dynamic changes in expression of genes, the products of which combat infectious microorganisms, initiate repair, and resolve inflammatory responses in cells and tissues. Recent evidence indicates that lncRNAs play important roles in directing the development of diverse immune cells and controlling the dynamic transcriptional programs that are a hallmark of immune cell activation. The importance of these molecules is underscored by their newly recognized roles in inflammatory diseases. In this review, we discuss the contribution of lncRNAs in the development and activation of immune cells and their roles in immune-related diseases. We also discuss challenges faced in identifying biological functions for this large and complex class of genes.
Annual Review of Immunology – Annual Reviews
Published: Apr 26, 2017
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.