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Association of Osteoarthritis and Functional Limitations With Cognitive Impairment Among Older Adults in the United States

Association of Osteoarthritis and Functional Limitations With Cognitive Impairment Among Older... Objective: Given overlapping pathophysiology, this study sought to assess the association between osteoarthritis (OA), functional impairment, and cognitive impairment in the aging population. Methods: The National Health and Nutrition Examination Survey was used to identify participants >60 years of age. We analyzed multivariable associations of grouped participants that underwent cognitive function testing using linear and logistic regression, adjusting for sex, age, race, and ethnicity. Results: Of 2776 identified participants representing a population of 50,242,917, 40% did not report OA or functional limitations; 21% had OA but not functional limitations; 15% did not have OA but had functional limitations; 17% had OA and related functional limitations; and 7% had OA and non-arthritic functional limitations. OA was not independently associated with cognitive impairment. Contrarily, functional limitations were associated with cognitive impairment regardless of OA diagnosis. Discussion: Cognitive impairment is not associated with OA, but rather functional limitations, potentially guiding future intervention. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Aging and Health SAGE

Association of Osteoarthritis and Functional Limitations With Cognitive Impairment Among Older Adults in the United States

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References (71)

Publisher
SAGE
Copyright
© The Author(s) 2023
ISSN
0898-2643
eISSN
1552-6887
DOI
10.1177/08982643231153459
Publisher site
See Article on Publisher Site

Abstract

Objective: Given overlapping pathophysiology, this study sought to assess the association between osteoarthritis (OA), functional impairment, and cognitive impairment in the aging population. Methods: The National Health and Nutrition Examination Survey was used to identify participants >60 years of age. We analyzed multivariable associations of grouped participants that underwent cognitive function testing using linear and logistic regression, adjusting for sex, age, race, and ethnicity. Results: Of 2776 identified participants representing a population of 50,242,917, 40% did not report OA or functional limitations; 21% had OA but not functional limitations; 15% did not have OA but had functional limitations; 17% had OA and related functional limitations; and 7% had OA and non-arthritic functional limitations. OA was not independently associated with cognitive impairment. Contrarily, functional limitations were associated with cognitive impairment regardless of OA diagnosis. Discussion: Cognitive impairment is not associated with OA, but rather functional limitations, potentially guiding future intervention.

Journal

Journal of Aging and HealthSAGE

Published: Oct 1, 2023

Keywords: osteoarthritis; cognitive impairment; functional limitations; aging; dementia

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