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The discovery of insulin

The discovery of insulin Anaesthesia Cover Note and Intensive Care Anaesthesia and Intensive Care 0(0) 1–3 ! The Author(s) 2023 Article reuse guidelines: sagepub.com/journals-permissions DOI: 10.1177/0310057X231158166 journals.sagepub.com/home/aic 1,2 3 Christine M Ball and Peter J Featherstone Cover photo. Insulin vials and packaging. Prepared by Connaught Laboratories, University of Toronto, 1924. Image courtesy of Sanofi Vaccines, Toronto Archives (formerly Connaught Laboratories). Captain Meredith of the Royal Artillery ‘came under physiology of healthful digestion be properly explained Dr Rollo’s care on the 16th of October 1796’. It was and established’. clear from his symptoms—excessive production of It would be many decades before ‘healthful diges- sweet-tasting urine, extreme thirst, weight loss and tion’ was properly understood. Over those years, while exhaustion—that he was suffering from diabetes melli- many diabetic adults were successfully treated with die- tus, a disease which had ‘in general resisted every tary restrictions, opium and bloodletting remained the remedy hitherto recommended for its removal’. The mainstays of medical therapy, along with a wide range treatment Rollo prescribed was drastic. It included a diet of animal protein, principally ‘game, and old meats which have been long kept ... fat and rancid old meats’, Monash University. Department of Anaesthesiology and Perioperative Medicine, Melbourne, Australia regular http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Anaesthesia and Intensive Care SAGE

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References (19)

Publisher
SAGE
Copyright
© The Author(s) 2023
ISSN
0310-057X
eISSN
1448-0271
DOI
10.1177/0310057x231158166
Publisher site
See Article on Publisher Site

Abstract

Anaesthesia Cover Note and Intensive Care Anaesthesia and Intensive Care 0(0) 1–3 ! The Author(s) 2023 Article reuse guidelines: sagepub.com/journals-permissions DOI: 10.1177/0310057X231158166 journals.sagepub.com/home/aic 1,2 3 Christine M Ball and Peter J Featherstone Cover photo. Insulin vials and packaging. Prepared by Connaught Laboratories, University of Toronto, 1924. Image courtesy of Sanofi Vaccines, Toronto Archives (formerly Connaught Laboratories). Captain Meredith of the Royal Artillery ‘came under physiology of healthful digestion be properly explained Dr Rollo’s care on the 16th of October 1796’. It was and established’. clear from his symptoms—excessive production of It would be many decades before ‘healthful diges- sweet-tasting urine, extreme thirst, weight loss and tion’ was properly understood. Over those years, while exhaustion—that he was suffering from diabetes melli- many diabetic adults were successfully treated with die- tus, a disease which had ‘in general resisted every tary restrictions, opium and bloodletting remained the remedy hitherto recommended for its removal’. The mainstays of medical therapy, along with a wide range treatment Rollo prescribed was drastic. It included a diet of animal protein, principally ‘game, and old meats which have been long kept ... fat and rancid old meats’, Monash University. Department of Anaesthesiology and Perioperative Medicine, Melbourne, Australia regular

Journal

Anaesthesia and Intensive CareSAGE

Published: May 1, 2023

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