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A Case Approach to Perioperative Drug-Drug InteractionsCYP2D6: Where It All Began

A Case Approach to Perioperative Drug-Drug Interactions: CYP2D6: Where It All Began [This chapter discusses the genetics, metabolic actions, substrates, and inhibitors of cytochrome P450 2D6.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Case Approach to Perioperative Drug-Drug InteractionsCYP2D6: Where It All Began

Editors: Marcucci, Catherine; Hutchens, Michael P.; Wittwer, Erica D.; Weingarten, Toby N.; Sprung, Juraj; Nicholson, Wayne T.; Lalwani, Kirk; Metro, David G.; Dull, Randal O.; Swide, Christopher E.; Seagull, F. Jacob; Kirsch, Jeffrey R.; Sandson, Neil B.

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References (15)

Publisher
Springer New York
Copyright
© Springer Science+Business Media New York 2015
ISBN
978-1-4614-7494-4
Pages
29 –32
DOI
10.1007/978-1-4614-7495-1_5
Publisher site
See Chapter on Publisher Site

Abstract

[This chapter discusses the genetics, metabolic actions, substrates, and inhibitors of cytochrome P450 2D6.]

Published: May 7, 2013

Keywords: Cytochrome P450; CYP2D6; CYP; Cytochrome; 2D6; Pharmacokinetic; Metabolism; Metabolic pathway; Monoxygenase; Liver; Intestine; Chromosome 22; Phenotype; Genotype; Phenotypic variability; Polymorphism; Allele; Wild type; Heterozygous; Homozygous; Poor metabolizer; Intermediate metabolizer; Rapid metabolizer; Ultrarapid metabolizer; Oxycodone; Beta-blockers; Dextromethorphan; Fluoxetine; Codeine; Tramadol; Prodrug; Morphine; Antiarrhythmics; SSRIs; Tricyclic antidepressants; Antipsychotics; Inhibitors; Substrates ritonavir; Bupropion; Goldenseal; Quinidine; Hydrocodone; Dihydrocodone; Ondansetron; Celecoxib; Diphenhydramine; Metoclopramide; Ropivacaine; Cimetidine; Methadone; Amiodarone

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