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[This chapter discusses the genetics, metabolic actions, substrates, and inhibitors of cytochrome P450 2D6.]
Published: May 7, 2013
Keywords: Cytochrome P450; CYP2D6; CYP; Cytochrome; 2D6; Pharmacokinetic; Metabolism; Metabolic pathway; Monoxygenase; Liver; Intestine; Chromosome 22; Phenotype; Genotype; Phenotypic variability; Polymorphism; Allele; Wild type; Heterozygous; Homozygous; Poor metabolizer; Intermediate metabolizer; Rapid metabolizer; Ultrarapid metabolizer; Oxycodone; Beta-blockers; Dextromethorphan; Fluoxetine; Codeine; Tramadol; Prodrug; Morphine; Antiarrhythmics; SSRIs; Tricyclic antidepressants; Antipsychotics; Inhibitors; Substrates ritonavir; Bupropion; Goldenseal; Quinidine; Hydrocodone; Dihydrocodone; Ondansetron; Celecoxib; Diphenhydramine; Metoclopramide; Ropivacaine; Cimetidine; Methadone; Amiodarone
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