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A Case-Based Guide to Clinical EndocrinologyProlactinoma in Pregnancy

A Case-Based Guide to Clinical Endocrinology: Prolactinoma in Pregnancy [Prolactinomas in pregnancy may present a medical challenge due to concerns about tumor growth during pregnancy from elevated circulating estrogen levels. It is generally recommended and accepted to stop dopamine agonists in pregnant patients with microprolactinomas or macroprolactinomas as long is there is no invasion or compression of surrounding sellar structures. Cabergoline and bromocriptine are FDA pregnancy category B and have been observed to be safe in pregnancy (including during organogenesis). Serum prolactin levels and pituitary MRI are not routinely needed during pregnancy unless clinical compressive symptoms develop. Pregnant patients with prolactinomas should be monitored at least once every trimester for the development of compressive symptoms.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Case-Based Guide to Clinical EndocrinologyProlactinoma in Pregnancy

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References (45)

Publisher
Springer International Publishing
Copyright
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
ISBN
978-3-030-84366-3
Pages
307 –315
DOI
10.1007/978-3-030-84367-0_34
Publisher site
See Chapter on Publisher Site

Abstract

[Prolactinomas in pregnancy may present a medical challenge due to concerns about tumor growth during pregnancy from elevated circulating estrogen levels. It is generally recommended and accepted to stop dopamine agonists in pregnant patients with microprolactinomas or macroprolactinomas as long is there is no invasion or compression of surrounding sellar structures. Cabergoline and bromocriptine are FDA pregnancy category B and have been observed to be safe in pregnancy (including during organogenesis). Serum prolactin levels and pituitary MRI are not routinely needed during pregnancy unless clinical compressive symptoms develop. Pregnant patients with prolactinomas should be monitored at least once every trimester for the development of compressive symptoms.]

Published: Jan 4, 2022

Keywords: Prolactinoma; Pregnancy; Hyperprolactinemia; Lactotroph; Cabergoline; Dopamine agonist; Pituitary tumor

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