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[This article reviews and comments various laboratory tests that are commonly used in the investigation and assessment of environmental and occupational lung diseases affecting both the lung parenchyma per se as well as the airways and caused by exposure to various organic and inorganic materials. These conditions include asbestosis and silicosis, asthma, and hypersensitivity pneumonitis. The tests that are reviewed are (1) general lung function tests: lung volumes, CO diffusion, exercise testing; (2) specialized lung function tests: assessment of nonspecific bronchial responsiveness with methacholine and other agents, serial assessments of airway caliber with peak expiratory flows; specific inhalation tests; (3) assessment of airway inflammation by induced sputum and exhaled NO. The clinical indications and methodology of these tests are presented and discussed.]
Published: Sep 19, 2012
Keywords: Occupational asthma; Asbestosis; Silicosis; Hypersensitivity pneumonitis
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