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A Clinician's Guide to Pemphigus VulgarisOverview of Diagnosis

A Clinician's Guide to Pemphigus Vulgaris: Overview of Diagnosis [Patients with pemphigus vulgaris (PV) are seen to initially suffer from oral erosions and then successively develop cutaneous involvement. Mucous membrane erosions precede cutaneous expressions of the disease and often result in a lengthened course of misdiagnosis with illnesses such as aphthous ulceration. As seen in some cases of PV, painful oral ulceration may appear to be the only indicator of the disease. Common mucosal surfaces that are involved in the manifestation of the disease include the gingiva, soft and hard palate, floor of the mouth, tongue, esophagus, oropharynx, nasal, larynx, urethra, vulva, and cervix. Conjunctiva involvement is less frequently observed in PV. PV patients also demonstrate dysphagia accompanied with weight loss.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Clinician's Guide to Pemphigus VulgarisOverview of Diagnosis

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Publisher
Springer International Publishing
Copyright
© Springer International Publishing AG 2018
ISBN
978-3-319-67758-3
Pages
21 –27
DOI
10.1007/978-3-319-67759-0_6
Publisher site
See Chapter on Publisher Site

Abstract

[Patients with pemphigus vulgaris (PV) are seen to initially suffer from oral erosions and then successively develop cutaneous involvement. Mucous membrane erosions precede cutaneous expressions of the disease and often result in a lengthened course of misdiagnosis with illnesses such as aphthous ulceration. As seen in some cases of PV, painful oral ulceration may appear to be the only indicator of the disease. Common mucosal surfaces that are involved in the manifestation of the disease include the gingiva, soft and hard palate, floor of the mouth, tongue, esophagus, oropharynx, nasal, larynx, urethra, vulva, and cervix. Conjunctiva involvement is less frequently observed in PV. PV patients also demonstrate dysphagia accompanied with weight loss.]

Published: Nov 27, 2017

Keywords: Diagnosis; Pemphigus vulgaris; Oral erosions; Skin lesions; Biopsy; Enzyme-linked immunosorbent assay (ELISA); Immunofluorescence; Histopathology

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