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[The aim of diagnostic and physiological tests in patients with presumed disorders of gastrointestinal function is to establish a firm diagnosis, which allows specific treatment. However, the number of efficacious and specific treatment modalities for disorders of gastrointestinal function is limited. Very often, the treating physician has to resort to the usage of drugs that were developed for other conditions (off-label use), which may lead to confusion and can be implicated in the occurrence of adverse events. To date, no cure is available for disorders of gastrointestinal function. The therapeutic aim when dealing with disorders of gastrointestinal function is to alleviate the symptom burden associated with these conditions. Treatment approaches are directed either toward changing the contractility of the gastrointestinal tract, its secretory activity, or decreasing sensitivity (perception) of the gastrointestinal tract (Fig. 3.1).]
Published: Jan 23, 2016
Keywords: Irritable Bowel Syndrome; Bile Salt; Cystic Fibrosis Transmembrane Conductance Regulator; Gastrointestinal Function; Isosorbide Dinitrate
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