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[During fasting, the stomach and small bowel exhibit a recurrent pattern of contractions and quiescence, which is called the migrating motor complex (MMC). A full MMC cycle lasts 90–120 min and comprises three phases (see Chap. 1). Phase 1 is a period of absence of contractions; during phase II contractions occur with highly variable frequency without apparent rigorous organization. Phase III is characterized by a period of 5–12 min of strong contractions at maximum frequency (3/min in the stomach, up to 12/min in the small intestine), followed again by phase I. This pattern starts proximally, in the stomach or the duodenum, and gradually moves aborally to the distal small bowel, to start again proximally. During the passage of phase III, nonabsorbable remnants are cleared from the antrum, and intestinal phase III ensures further evacuation of small bowel content into the large intestine. This activity is referred to as the intestinal housekeeper function of the MMC.]
Published: Jan 23, 2016
Keywords: Small Bowel; Irritable Bowel Syndrome; Functional Dyspepsia; Small Intestinal Bacterial Overgrowth; Mitochondrial Myopathy
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