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A Guide to Methods in the Biomedical SciencesDetection and Analysis of Proteins

A Guide to Methods in the Biomedical Sciences: Detection and Analysis of Proteins Chapter 1 A. Introduction Proteins are the body’s building blocks. They are the second most abundant part of our bodies, comprising about 20% of our weight (the most abundant constituent, water, accounts for 70%). Proteins make up muscles, most of our enzymes are proteins, and the antibodies that protect us from pathogens are glycoproteins, or proteins that also contain carbohydrate sidechains. Proteins are biopolymers that consist of various mixtures of the 20 amino acids. The word “protein” is de- rived from a Greek root meaning “of first importance”. Proteins were discovered in 1838 by Jöns Jacob Berzelius (1779–1848), a Swedish chemist. Berzelius also developed a system of chemical notation that is essentially the same basic system used today. Berzelius is one of three chemists who are considered the fathers of modern chemistry. The other two chemists are Antoine Levoisier (1743–1794) and John Dalton (1766–1844). Levoisier was the first to articulate and experi- mentally demonstrate the idea of the conservation of matter. He used quantitative methods to measure products of chemical reactions, allow- ing the composition of compounds to be determined with considerable accuracy. Levoisier also had the distinction of losing his head (literally!) during the French Revolution. John Dalton http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Guide to Methods in the Biomedical SciencesDetection and Analysis of Proteins

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Publisher
Springer US
Copyright
© Springer Science + Business Media, Inc. 2005
ISBN
978-0-387-22844-0
Pages
1 –24
DOI
10.1007/0-387-22845-4_1
Publisher site
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Abstract

Chapter 1 A. Introduction Proteins are the body’s building blocks. They are the second most abundant part of our bodies, comprising about 20% of our weight (the most abundant constituent, water, accounts for 70%). Proteins make up muscles, most of our enzymes are proteins, and the antibodies that protect us from pathogens are glycoproteins, or proteins that also contain carbohydrate sidechains. Proteins are biopolymers that consist of various mixtures of the 20 amino acids. The word “protein” is de- rived from a Greek root meaning “of first importance”. Proteins were discovered in 1838 by Jöns Jacob Berzelius (1779–1848), a Swedish chemist. Berzelius also developed a system of chemical notation that is essentially the same basic system used today. Berzelius is one of three chemists who are considered the fathers of modern chemistry. The other two chemists are Antoine Levoisier (1743–1794) and John Dalton (1766–1844). Levoisier was the first to articulate and experi- mentally demonstrate the idea of the conservation of matter. He used quantitative methods to measure products of chemical reactions, allow- ing the composition of compounds to be determined with considerable accuracy. Levoisier also had the distinction of losing his head (literally!) during the French Revolution. John Dalton

Published: Jan 1, 2005

Keywords: Nuclear Magnetic Resonance; Fluorescence Resonance Energy Transfer; Nobel Prize; Biomedical Science; Sucrose Density Gradient

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