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A Handbook of Transcription FactorsA Catalogue of Eukaryotic Transcription Factor Types, Their Evolutionary Origin, and Species Distribution

A Handbook of Transcription Factors: A Catalogue of Eukaryotic Transcription Factor Types, Their... [Transcription factors (TFs) play key roles in the regulation of gene expression by binding in a sequence-specific manner to genomic DNA. In eukaryotes, DNA binding is achieved by a wide range of structural forms and motifs. TFs are typically classified by their DNA-binding domain (DBD) type. In this chapter, we catalogue and survey 91 different TF DBD types in metazoa, plants, fungi, and protists. We briefly discuss well-characterized TF families representing the major DBD superclasses. We also examine the species distributions and inferred evolutionary histories of the various families, and the potential roles played by TF family expansion and dimerization.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Handbook of Transcription FactorsA Catalogue of Eukaryotic Transcription Factor Types, Their Evolutionary Origin, and Species Distribution

Part of the Subcellular Biochemistry Book Series (volume 52)
Editors: Hughes, Timothy R.
Weirauch, Matthew T.; Hughes, T.R.
A Handbook of Transcription Factors — Apr 14, 2011
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Publisher
Springer Netherlands
Copyright
© Springer Science+Business Media B.V. 2011
ISBN
978-90-481-9068-3
Pages
25 –73
DOI
10.1007/978-90-481-9069-0_3
Publisher site
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Abstract

[Transcription factors (TFs) play key roles in the regulation of gene expression by binding in a sequence-specific manner to genomic DNA. In eukaryotes, DNA binding is achieved by a wide range of structural forms and motifs. TFs are typically classified by their DNA-binding domain (DBD) type. In this chapter, we catalogue and survey 91 different TF DBD types in metazoa, plants, fungi, and protists. We briefly discuss well-characterized TF families representing the major DBD superclasses. We also examine the species distributions and inferred evolutionary histories of the various families, and the potential roles played by TF family expansion and dimerization.]

Published: Apr 14, 2011

Keywords: Transcription factor; DNA-binding domain; Evolution

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