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A Life Course Perspective on Health Trajectories and TransitionsA Life Course Perspective on Body Size and Cardio-metabolic Health

A Life Course Perspective on Health Trajectories and Transitions: A Life Course Perspective on... [The growth of a child and the amount of weight gained across the life course is associated with risk for many chronic degenerative diseases. The life course approach to this area of epidemiological research has burgeoned over the last 25 years, since the initial observation of an inverse relationship between birth weight and coronary heart disease. We review the substantial amount of published research to demonstrate which age-related body size trajectories are indicative of increased risk of cardio-metabolic diseases such as coronary heart disease, stroke, and type two diabetes. Association does not mean causation. The chapter thus also provides an overview of the key sociocultural and other factors responsible for deleterious trajectories, and the biological pathways through which they act, to show how the trajectories are driven by biology but modifiable by the environment. Attention is paid to critical periods and transitions, both biological (e.g., puberty) and behavioural (e.g., marriage), and the influences that these might have on an individual’s trajectory. We highlight the importance of life course trajectories of body size and their associations with trajectories of markers of cardio-metabolic health such as blood pressure and lipids, and the need to integrate biological and social research to move towards a more complete understanding of cardio-metabolic disease processes and, ultimately, how to delay the onset of disease.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Life Course Perspective on Health Trajectories and TransitionsA Life Course Perspective on Body Size and Cardio-metabolic Health

Part of the Life Course Research and Social Policies Book Series (volume 4)
Editors: Burton-Jeangros, Claudine; Cullati, Stéphane; Sacker, Amanda; Blane, David
Johnson, William; Kuh, Diana; Hardy, Rebecca
A Life Course Perspective on Health Trajectories and Transitions — May 19, 2015
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References (156)

Publisher
Springer International Publishing
Copyright
© The Editor(s) and the Author(s) 2015
ISBN
978-3-319-20483-3
Pages
61 –83
DOI
10.1007/978-3-319-20484-0_4
Publisher site
See Chapter on Publisher Site

Abstract

[The growth of a child and the amount of weight gained across the life course is associated with risk for many chronic degenerative diseases. The life course approach to this area of epidemiological research has burgeoned over the last 25 years, since the initial observation of an inverse relationship between birth weight and coronary heart disease. We review the substantial amount of published research to demonstrate which age-related body size trajectories are indicative of increased risk of cardio-metabolic diseases such as coronary heart disease, stroke, and type two diabetes. Association does not mean causation. The chapter thus also provides an overview of the key sociocultural and other factors responsible for deleterious trajectories, and the biological pathways through which they act, to show how the trajectories are driven by biology but modifiable by the environment. Attention is paid to critical periods and transitions, both biological (e.g., puberty) and behavioural (e.g., marriage), and the influences that these might have on an individual’s trajectory. We highlight the importance of life course trajectories of body size and their associations with trajectories of markers of cardio-metabolic health such as blood pressure and lipids, and the need to integrate biological and social research to move towards a more complete understanding of cardio-metabolic disease processes and, ultimately, how to delay the onset of disease.]

Published: May 19, 2015

Keywords: Coronary Heart Disease; Sensitive Period; Coronary Heart Disease Mortality; Rapid Weight Gain; Increase Disease Risk

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