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[Ubiquitous gaps between product efficacy in clinical trials and their real-world effectiveness suggest the need for evidence to bridge the research-to-practice divide. We conducted an innovative interdisciplinary project using a sequential mixed methods design to explore the social ecology of the acceptability of rectal microbicides (products in development to be applied to the rectal mucosa to reduce the risk of HIV acquisition), among young gay and bisexual men (GBM) and transgender women. The research was carried out in Thailand, which is the site of an explosive HIV epidemic among GBM. In collaboration with community-based organizations, we implemented focus groups to elicit in depth discussions of rectal microbicide preferences in the context of sexual practices, relationships, and sex work. We applied innovative data collection and data analytic methods, which allowed us to use focus group results to determine and understand rectal microbicide attributes modeled in a subsequent discrete choice experiment.]
Published: Jun 24, 2017
Keywords: HIV prevention; Rectal microbicide; Gay men; Transgender women; Thailand; Mixed methods
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