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A Picture is Worth a Thousand TablesGraphical Displays for Biomarker Data

A Picture is Worth a Thousand Tables: Graphical Displays for Biomarker Data [Analysis of high-dimensional biomarker data is in general of exploratory nature and aims to discover or dissect subgroups of patients sharing a specific pattern of biomarker measurements. One major challenge is to extract the relevant markers from the extremely large pool of measured markers. Specific techniques such as grouping and ordering and dimension reduction allow to aggregate huge amounts of data into single meaningful graphics. These graphics can guide the direction of exploration during the analysis. We present graphical tools for unsupervised and supervised objectives based on gene expression data of multiple myeloma patients which are part of the MAQC-II project.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Picture is Worth a Thousand TablesGraphical Displays for Biomarker Data

Editors: Krause, Andreas; O'Connell, Michael

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References (31)

Publisher
Springer US
Copyright
© Springer Science+Business Media, New York 2012
ISBN
978-1-4614-5328-4
Pages
139 –169
DOI
10.1007/978-1-4614-5329-1_8
Publisher site
See Chapter on Publisher Site

Abstract

[Analysis of high-dimensional biomarker data is in general of exploratory nature and aims to discover or dissect subgroups of patients sharing a specific pattern of biomarker measurements. One major challenge is to extract the relevant markers from the extremely large pool of measured markers. Specific techniques such as grouping and ordering and dimension reduction allow to aggregate huge amounts of data into single meaningful graphics. These graphics can guide the direction of exploration during the analysis. We present graphical tools for unsupervised and supervised objectives based on gene expression data of multiple myeloma patients which are part of the MAQC-II project.]

Published: Sep 28, 2012

Keywords: High-dimensional; Biomarker; Genomic

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