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N. Veronese, M. Solmi, W. Rizza, E. Manzato, G. Sergi, P. Santonastaso, L. Caregaro, A. Favaro, C. Correll (2015)
Vitamin D status in anorexia nervosa: A meta-analysis.The International journal of eating disorders, 48 7
H. McKay, Danmei Liu, Deetria Egeli, S. Boyd, M. Burrows (2011)
Physical activity positively predicts bone architecture and bone strength in adolescent males and femalesActa Paediatrica, 100
Neville Golden, L. Lanzkowsky, J. Schebendach, C. Palestro, M. Jacobson, I. Shenker (2002)
The effect of estrogen-progestin treatment on bone mineral density in anorexia nervosa.Journal of pediatric and adolescent gynecology, 15 3
M. Misra, N. Golden, D. Katzman (2016)
State of the art systematic review of bone disease in anorexia nervosa.The International journal of eating disorders, 49 3
D. Bailey, Alan Martin, H. McKay, S. Whiting, R. Mirwald (2000)
Calcium Accretion in Girls and Boys During Puberty: A Longitudinal AnalysisJournal of Bone and Mineral Research, 15
M. Misra, R. Prabhakaran, K. Miller, M. Goldstein, D. Mickley, Laura Clauss, P. Lockhart, J. Cord, D. Herzog, D. Katzman, A. Klibanski (2008)
Weight gain and restoration of menses as predictors of bone mineral density change in adolescent girls with anorexia nervosa-1.The Journal of clinical endocrinology and metabolism, 93 4
Neville Golden, P. Kreitzer, Marc Jacobson, Fred Chasalow, Janet Schebendach, Samuel Freedman, I. Shenker (1994)
Disturbances in growth hormone secretion and action in adolescents with anorexia nervosa.The Journal of pediatrics, 125 4
K. Ecklund, S. Vajapeyam, H. Feldman, C. Buzney, R. Mulkern, P. Kleinman, C. Rosen, C. Gordon (2009)
Bone Marrow Changes in Adolescent Girls With Anorexia NervosaJournal of Bone and Mineral Research, 25
M. Ghoch, C. Milanese, S. Calugi, M. Müller, M. Pourhassan, A. Ruocco, R. Grave (2015)
Regional fat distribution in adolescent and adult females with anorexia nervosa: A longitudinal study.Clinical nutrition, 34 6
L. Bachrach, D. Katzman, I. Litt, D. Guido, R. Marcus (1991)
Recovery from osteopenia in adolescent girls with anorexia nervosa.The Journal of clinical endocrinology and metabolism, 72 3
M. Solmi, N. Veronese, C. Correll, C. Correll, A. Favaro, P. Santonastaso, L. Caregaro, D. Vancampfort, C. Luchini, M. Hert, B. Stubbs, B. Stubbs (2016)
Bone mineral density, osteoporosis, and fractures among people with eating disorders: a systematic review and meta‐analysisActa Psychiatrica Scandinavica, 133
A. Faje, P. Fazeli, K. Miller, D. Katzman, Seda Ebrahimi, Hang Lee, Nara Mendes, Deirdre Snelgrove, E. Meenaghan, M. Misra, A. Klibanski (2014)
Fracture risk and areal bone mineral density in adolescent females with anorexia nervosa.The International journal of eating disorders, 47 5
M. Bredella, P. Fazeli, K. Miller, M. Misra, M. Torriani, Bijoy Thomas, R. Ghomi, C. Rosen, A. Klibanski (2009)
Increased bone marrow fat in anorexia nervosa.The Journal of clinical endocrinology and metabolism, 94 6
A. Faje, L. Karim, Alexander Taylor, Hang Lee, K. Miller, Nara Mendes, E. Meenaghan, M. Goldstein, M. Bouxsein, M. Misra, A. Klibanski (2013)
Adolescent girls with anorexia nervosa have impaired cortical and trabecular microarchitecture and lower estimated bone strength at the distal radius.The Journal of clinical endocrinology and metabolism, 98 5
J. Castro, J. Toro, L. Lázaro, F. Pons, I. Halperin (2002)
Bone mineral density in male adolescents with anorexia nervosa.Journal of the American Academy of Child and Adolescent Psychiatry, 41 5
F. Smink, D. Hoeken, A. Oldehinkel, H. Hoek (2014)
Prevalence and severity of DSM-5 eating disorders in a community cohort of adolescents.The International journal of eating disorders, 47 6
Karla Christo, R. Prabhakaran, Brooke Lamparello, J. Cord, K. Miller, M. Goldstein, Nupur Gupta, D. Herzog, A. Klibanski, M. Misra (2008)
Bone Metabolism in Adolescent Athletes With Amenorrhea, Athletes With Eumenorrhea, and Control SubjectsPediatrics, 121
Jason Nagata, N. Golden, M. Leonard, Lawrence Copelovitch, M. Denburg (2017)
Assessment of Sex Differences in Fracture Risk Among Patients With Anorexia Nervosa: A Population‐Based Cohort Study Using The Health Improvement NetworkJournal of Bone and Mineral Research, 32
P. Vestergaard, C. Emborg, R. Støving, C. Hagen, L. Mosekilde, K. Brixen (2002)
Fractures in patients with anorexia nervosa, bulimia nervosa, and other eating disorders--a nationwide register study.The International journal of eating disorders, 32 3
B. Biller, Velia Saxe, David Herzog, Daniel Rosenthal, Susan Holzman, A. Klibanski (1989)
Mechanisms of osteoporosis in adult and adolescent women with anorexia nervosa.The Journal of clinical endocrinology and metabolism, 68 3
A. DiVasta, H. Feldman, T. Beck, M. LeBoff, Catherine Gordon (2014)
Does Hormone Replacement Normalize Bone Geometry in Adolescents With Anorexia Nervosa?Journal of Bone and Mineral Research, 29
Steven Grinspoon, Karen Miller, Caryn Coyle, Judy Krempin, Catharina Armstrong, Sarah Pitts, David Herzog, A. Klibanski (1999)
Severity of osteopenia in estrogen-deficient women with anorexia nervosa and hypothalamic amenorrhea.The Journal of clinical endocrinology and metabolism, 84 6
S. Grinspoon, E. Thomas, S. Pitts, E. Gross, D. Mickley, K. Miller, D. Herzog, A. Klibanski (2000)
Prevalence and Predictive Factors for Regional Osteopenia in Women with Anorexia NervosaAnnals of Internal Medicine, 133
Josefina Castro, Luisa Lázaro, Francesca Pons, Irene Halperin, J. Toro (2000)
Predictors of bone mineral density reduction in adolescents with anorexia nervosa.Journal of the American Academy of Child and Adolescent Psychiatry, 39 11
M. Misra, D. Katzman, K. Miller, Nara Mendes, Deirdre Snelgrove, Melissa Russell, M. Goldstein, Seda Ebrahimi, Laura Clauss, Thomas Weigel, D. Mickley, D. Schoenfeld, D. Herzog, A. Klibanski (2011)
Physiologic estrogen replacement increases bone density in adolescent girls with anorexia nervosaJournal of Bone and Mineral Research, 26
Anne Ward, Nigel Brown, Janet Treasure (1997)
Persistent osteopenia after recovery from anorexia nervosa.The International journal of eating disorders, 22 1
Maria Monge, S. Forman, Nicole McKenzie, D. Rosen, Kathleen Mammel, S. Callahan, Rebecca Hehn, E. Rome, C. Kapphahn, J. Carlson, Mary Romano, Joan Malizio, T. Bravender, E. Sigel, M. Rouse, Dionne Graham, M. Jay, A. Hergenroeder, M. Fisher, N. Golden, E. Woods (2013)
Use of Psychopharmacologic Medications in Adolescents With Restrictive Eating Disorders: Analysis of Data From the National Eating Disorder Quality Improvement Collaborative.The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 57 1
Alexandra Haagensen, Henry Feldman, Julie Ringelheim, Catherine Gordon (2008)
Low prevalence of vitamin D deficiency among adolescents with anorexia nervosaOsteoporosis International, 19
W. Herzog, H. Minne, C. Deter, G. Leidig, D. Schellberg, C. Wüster, Rainer Gronwald, E. Sarembe, F. Kröger, G. Bergmann, E. Petzold, P. Hahn, H. Schepank, R. Ziegler (1993)
Outcome of bone mineral density in anorexia nervosa patients 11.7 years after first admissionJournal of Bone and Mineral Research, 8
Jason Nagata, N. Golden, Rebecka Peebles, J. Long, M. Leonard, Audrey Chang, J. Carlson (2016)
Assessment of sex differences in bone deficits among adolescents with anorexia nervosaInternational Journal of Eating Disorders, 50
A. DiVasta, H. Feldman, Courtney Giancaterino, C. Rosen, M. LeBoff, C. Gordon (2012)
The effect of gonadal and adrenal steroid therapy on skeletal health in adolescents and young women with anorexia nervosa.Metabolism: clinical and experimental, 61 7
M. Misra, D. Katzman, J. Cord, S. Manning, Nara Mendes, D. Herzog, K. Miller, A. Klibanski (2008)
Bone metabolism in adolescent boys with anorexia nervosa.The Journal of clinical endocrinology and metabolism, 93 8
D. Gatti, M. Ghoch, O. Viapiana, A. Ruocco, E. Chignola, M. Rossini, A. Giollo, L. Idolazzi, S. Adami, R. Grave (2015)
Strong relationship between vitamin D status and bone mineral density in anorexia nervosa.Bone, 78
S. Grinspoon, H. Baum, Kristen Lee, E. Anderson, D. Herzog, A. Klibanski (1996)
Effects of short-term recombinant human insulin-like growth factor I administration on bone turnover in osteopenic women with anorexia nervosa.The Journal of clinical endocrinology and metabolism, 81 11
G. Strokosch, A. Friedman, Shu-chen Wu, M. Kamin (2006)
Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in adolescent females with anorexia nervosa: a double-blind, placebo-controlled study.The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 39 6
K. Miller, E. Meenaghan, E. Lawson, M. Misra, Suzanne Gleysteen, D. Schoenfeld, D. Herzog, A. Klibanski (2011)
Effects of risedronate and low-dose transdermal testosterone on bone mineral density in women with anorexia nervosa: a randomized, placebo-controlled study.The Journal of clinical endocrinology and metabolism, 96 7
Neville Golden, E. Iglesias, M. Jacobson, D. Carey, Wendy Meyer, J. Schebendach, Stanley Hertz, I. Shenker (2005)
Alendronate for the treatment of osteopenia in anorexia nervosa: a randomized, double-blind, placebo-controlled trial.The Journal of clinical endocrinology and metabolism, 90 6
H. McKay, M. Petit, R. Schutz, J. Prior, S. Barr, K. Khan (2000)
Augmented trochanteric bone mineral density after modified physical education classes: a randomized school-based exercise intervention study in prepubescent and early pubescent children.The Journal of pediatrics, 136 2
M. Misra, Marie Clair, Nara Mendes, K. Miller, E. Lawson, E. Meenaghan, Thomas Weigel, Seda Ebrahimi, D. Herzog, A. Klibanski (2010)
Use of SSRIs May Impact Bone Density in Adolescent and Young Women With Anorexia NervosaCNS Spectrums, 15
N. Rigotti, R. Neer, Steven Skates, David Herzog, Samuel Nussbaum (1991)
The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass.JAMA, 265 9
L. Sim, L. McGovern, Mohamed Elamin, B. Swiglo, P. Erwin, V. Montori (2009)
Effect on bone health of estrogen preparations in premenopausal women with anorexia nervosa: a systematic review and meta-analyses.The International journal of eating disorders, 43 3
P. Fazeli, I. Wang, K. Miller, D. Herzog, M. Misra, Hang Lee, J. Finkelstein, M. Bouxsein, A. Klibanski (2014)
Teriparatide increases bone formation and bone mineral density in adult women with anorexia nervosa.The Journal of clinical endocrinology and metabolism, 99 4
S. Naessén, K. Carlström, R. Glant, H. Jacobsson, A. Hirschberg (2006)
Bone mineral density in bulimic women--influence of endocrine factors and previous anorexia.European journal of endocrinology, 155 2
K. Miller, E. Lee, E. Lawson, M. Misra, Jennifer Minihan, S. Grinspoon, Suzanne Gleysteen, D. Mickley, D. Herzog, A. Klibanski (2006)
Determinants of skeletal loss and recovery in anorexia nervosa.The Journal of clinical endocrinology and metabolism, 91 8
S. Martin, L. Bachrach, N. Golden (2017)
Controlled Pilot Study of High-Impact Low-Frequency Exercise on Bone Loss and Vital-Sign Stabilization in Adolescents With Eating Disorders.The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 60 1
M. Misra, K. Miller, C. Almazan, Kavitha Ramaswamy, W. Lapcharoensap, M. Worley, G. Neubauer, D. Herzog, A. Klibanski (2003)
Alterations in cortisol secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism.The Journal of clinical endocrinology and metabolism, 89 10
A. Jamieson, A. Pelosi (2016)
Use of Denosumab in a Patient with Chronic Anorexia Nervosa and Osteoporosis.The American journal of medicine, 129 2
Catherine Gordon, E. Grace, S. Emans, H. Feldman, E. Goodman, Kelly Becker, C. Rosen, C. Gundberg, M. LeBoff (2002)
Effects of oral dehydroepiandrosterone on bone density in young women with anorexia nervosa: a randomized trial.The Journal of clinical endocrinology and metabolism, 87 11
D. Modan-Moses, Y. Levy-Shraga, O. Pinhas‐Hamiel, B. Kochavi, A. Enoch-Levy, I. Vered, D. Stein (2015)
High prevalence of vitamin D deficiency and insufficiency in adolescent inpatients diagnosed with eating disorders.The International journal of eating disorders, 48 6
L. Soyka, M. Misra, Aparna Frenchman, K. Miller, S. Grinspoon, D. Schoenfeld, A. Klibanski (2002)
Abnormal bone mineral accrual in adolescent girls with anorexia nervosa.The Journal of clinical endocrinology and metabolism, 87 9
M. Fisher, David Rosen, Rollyn Ornstein, Kathleen Mammel, D. Katzman, E. Rome, S. Callahan, Joan Malizio, Sarah Kearney, B. Walsh (2014)
Characteristics of avoidant/restrictive food intake disorder in children and adolescents: a "new disorder" in DSM-5.The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 55 1
S. Grinspoon, L. Thomas, K. Miller, D. Herzog, A. Klibanski (2002)
Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa.The Journal of clinical endocrinology and metabolism, 87 6
J. Turner, M. Bulsara, B. McDermott, G. Byrne, R. Prince, D. Forbes (2001)
Predictors of low bone density in young adolescent females with anorexia nervosa and other dieting disorders.The International journal of eating disorders, 30 3
L. Bachrach, D. Guido, D. Katzman, I. Litt, R. Marcus (1990)
Decreased bone density in adolescent girls with anorexia nervosa.Pediatrics, 86 3
T. Nakahara, N. Nagai, Muneki Tanaka, Tetsuro Muranaga, Shinya Kojima, S. Nozoe, T. Naruo (2006)
The effects of bone therapy on tibial bone loss in young women with anorexia nervosa.The International journal of eating disorders, 39 1
N. Golden, S. Abrams (2014)
Optimizing Bone Health in Children and AdolescentsPediatrics, 134
A. DiVasta, H. Feldman, Ashley Quach, M. Balestrino, C. Gordon (2009)
The effect of bed rest on bone turnover in young women hospitalized for anorexia nervosa: a pilot study.The Journal of clinical endocrinology and metabolism, 94 5
A. Lucas, L. Melton, C. Crowson, W. O'Fallon (1999)
Long-term fracture risk among women with anorexia nervosa: a population-based cohort study.Mayo Clinic proceedings, 74 10
The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 1999 by The Endocrine Society The Effects of Anorexia Nervosa on Bone Metabolism in Female Adolescents*
M. Misra, A. Aggarwal, K. Miller, C. Almazan, M. Worley, L. Soyka, D. Herzog, A. Klibanski (2004)
Effects of Anorexia Nervosa on Clinical, Hematologic, Biochemical, and Bone Density Parameters in Community-Dwelling Adolescent GirlsPediatrics, 114
D. Hartman, Arthur Crisp, Barbara Rooney, Chloe Rackow, Richard Atkinson, Sanjeev Patel (2000)
Bone density of women who have recovered from anorexia nervosa.The International journal of eating disorders, 28 1
Katherine Bachmann, Melanie Schorr, Alexander Bruno, M. Bredella, E. Lawson, C. Gill, V. Singhal, E. Meenaghan, A. Gerweck, Meghan Slattery, Kamryn Eddy, Seda Ebrahimi, Stuart Koman, J. Greenblatt, Robert Keane, Thomas Weigel, M. Misra, M. Bouxsein, A. Klibanski, K. Miller (2016)
Vertebral Volumetric Bone Density and Strength Are Impaired in Women With Low-Weight and Atypical Anorexia NervosaThe Journal of Clinical Endocrinology & Metabolism, 102
N. Golden, D. Katzman, S. Sawyer, Rollyn Ornstein, E. Rome, A. Garber, M. Kohn, R. Kreipe (2015)
Update on the medical management of eating disorders in adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 56 4
A. Klibanski, B. Biller, D. Schoenfeld, D. Herzog, Velia Saxe (1995)
The effects of estrogen administration on trabecular bone loss in young women with anorexia nervosa.The Journal of clinical endocrinology and metabolism, 80 3
[Impaired bone health with increased bone fragility is a potentially irreversible complication of eating disorders. Onset of an eating disorder is usually during adolescence, the critical time when peak bone mass is accrued. Adolescents with eating disorders have reduced bone mineral accrual, as well as accelerated bone resorption. Treatment of low bone mineral density remains challenging. Weight gain with resumption of spontaneous menses is associated with increases in bone mineral density, but residual deficits persist. As weight restoration is often a slow process, therapeutic strategies are needed to preserve bone mineral density during eating disorder treatment. Oral estrogen-progestin agents do not increase bone mineral density in adolescents with eating disorders, but physiological doses of transdermal estrogen with cyclic progestin may benefit some patients. The bisphosphonates are effective in adults, but concern about their efficacy and safety in adolescents limits their use. The future role of anabolic agents, bisphosphonates, and other antiresorptive agents remains to be determined. Current recommendations include weight restoration with resumption of spontaneous menses, moderate weight-bearing exercise, optimal calcium and vitamin D intake, and treatment of vitamin D deficiency.]
Published: Feb 10, 2018
Keywords: Adolescents; Eating disorders; Anorexia nervosa; Bone mineral density; Estrogen; Bisphosphonates; Calcium; Vitamin D
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