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A Practical Guide to Human Cancer GeneticsCardiorespiratory System and Thorax

A Practical Guide to Human Cancer Genetics: Cardiorespiratory System and Thorax [Squamous carcinomas of the head and neck (a grouping which includes tongue and mouth, nasopharynx, and larynx) are associated with cigarette smoking and alcohol ingestion (although the risk factors for different sites may differ). In addition, infection with human papillomavirus (HPV) is associated with cancers of the oropharynx (D’Souza et al. 2007). Specific head and neck cancers may be associated with familial cancer syndromes such as hereditary non-polyposis colon cancer syndrome and Li–Fraumeni syndrome (larynx) and Fanconi anemia (oral cancer). Foulkes et al. (1996) reported a relative risk of 3.7 for developing head and neck cancer in first-degree relatives of an affected case, but the relative risk was almost 8 if the index case had multiple primaries.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Practical Guide to Human Cancer GeneticsCardiorespiratory System and Thorax

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Publisher
Springer London
Copyright
© Springer-Verlag London 2014. Previous edition published by Cambridge University Press, 2007
ISBN
978-1-4471-2374-3
Pages
25 –30
DOI
10.1007/978-1-4471-2375-0_3
Publisher site
See Chapter on Publisher Site

Abstract

[Squamous carcinomas of the head and neck (a grouping which includes tongue and mouth, nasopharynx, and larynx) are associated with cigarette smoking and alcohol ingestion (although the risk factors for different sites may differ). In addition, infection with human papillomavirus (HPV) is associated with cancers of the oropharynx (D’Souza et al. 2007). Specific head and neck cancers may be associated with familial cancer syndromes such as hereditary non-polyposis colon cancer syndrome and Li–Fraumeni syndrome (larynx) and Fanconi anemia (oral cancer). Foulkes et al. (1996) reported a relative risk of 3.7 for developing head and neck cancer in first-degree relatives of an affected case, but the relative risk was almost 8 if the index case had multiple primaries.]

Published: Aug 14, 2013

Keywords: Lung Cancer; Lynch Syndrome; Nasopharyngeal Carcinoma; Fanconi Anemia; Lung Cancer Risk

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