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A Primer of Neuroimmunological DiseaseMultiple Sclerosis: Diagnosis

A Primer of Neuroimmunological Disease: Multiple Sclerosis: Diagnosis [There is no specific diagnostic test for MS. The diagnosis is usually made on the basis of a characteristic constellation of symptoms, signs, and laboratory findings. There are no diagnostic criteria that are both universally accepted and that neurologists invariably utilize in their day-to-day practice. Given the complexity of the central nervous system, it is not surprising that many problems arise when the MS patient presents with symptoms early in the course of the disease. There are frequent false-positive and false-negative findings, even by neurologists experienced in MS. The difficulties in diagnosis lead to anxiety among patients and their families during the evaluation period. The careful neurologist always makes the diagnosis of MS provisionally even in apparently obvious cases, assessing the odds over time, with the probability of MS always being less than 100%. Complete certainty is neither possible nor necessary to make the diagnosis of “definite MS.”] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Primer of Neuroimmunological DiseaseMultiple Sclerosis: Diagnosis

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Publisher
Springer US
Copyright
© Springer Science+Business Media, LLC 2012
ISBN
978-1-4614-2187-0
Pages
49 –55
DOI
10.1007/978-1-4614-2188-7_5
Publisher site
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Abstract

[There is no specific diagnostic test for MS. The diagnosis is usually made on the basis of a characteristic constellation of symptoms, signs, and laboratory findings. There are no diagnostic criteria that are both universally accepted and that neurologists invariably utilize in their day-to-day practice. Given the complexity of the central nervous system, it is not surprising that many problems arise when the MS patient presents with symptoms early in the course of the disease. There are frequent false-positive and false-negative findings, even by neurologists experienced in MS. The difficulties in diagnosis lead to anxiety among patients and their families during the evaluation period. The careful neurologist always makes the diagnosis of MS provisionally even in apparently obvious cases, assessing the odds over time, with the probability of MS always being less than 100%. Complete certainty is neither possible nor necessary to make the diagnosis of “definite MS.”]

Published: Jan 17, 2012

Keywords: Lyme Disease; Optic Neuritis; White Matter Lesion; Clinically Isolate Syndrome; McDonald Criterion

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