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Introduction 1 In cats it was demonstrated that after reimplantation of the ventral rootlets (Hoff- mann et al. 1993,1996), or after reimplantation of an autologous transplant between spinal cord and ruptured nerve (Holtzer 2003), regeneration of the motoneurons in the cervical spinal cord occurs. To reimplant rootlets or transplants into the spinal cord, a small longitudinal incision has to be made in the motor pathway area, whereby the rootlets leave the spinal cord (Hoffmann 1993; Holtzer 2003). Gaining insight into the consequences of such a longitudinal wound in the human spinal cord is necessary before reimplantation of avulsed rootlets or an autolo- gous transplant can be performed in man (Thomeer et al. 2002). A reexamination of the ascending systems in the human anterolateral funiculus, therefore, is one of the prerequisites to be carried out before adapting animal transplantation or reimplantation operations to man. A second, more technical, approach in the restoration of damage in the human central nervous system is Functional Electrical Stimulation (FES). Cortex and nu- cleus subthalamicus stimulation in Parkinson’s disease or spinal cord stimulation in chronic, intractable pain of neurogenic origin are examples in which FES is now applied in man. Renewed interest in the involved
Published: Jan 1, 2005
Keywords: Spinal Cord; Vagus Nerve Stimulation; Spinal Cord Stimulation; Potassium Dichromate; Functional Electrical Stimulation
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