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A Revised Consent Model for the Transplantation of Face and Upper Limbs: Covenant ConsentVascularized Composite Allotransplantation

A Revised Consent Model for the Transplantation of Face and Upper Limbs: Covenant Consent:... [In order to discuss the ethics of vascularized composite allotransplantation (VCA)Vascularized Composite Allotransplantation (VCA), it is necessary to have a firm grasp of this rapidly developing field, including its history, its present state and its anticipated future directions. The story of the development of VCA began in the imaginations of ancient peoples, but required important medical and surgical advances for the practice to become a reality. A survey of the history of VCAVascularized Composite Allotransplantation (VCA) will emphasize the role of advances in surgical techniques, including anastomosisAnastomosis of blood vessels and nerves and the emergence of microsurgeryMicrosurgery. It will also review the emergence of a better understanding of immunology and the development of effective means of immunosuppressionImmunosuppression. A brief survey of the beginnings of solid organ transplantationSolid Organ Transplantation (SOT) and limb replantationLimb replantation will be offered, as they together formed the technical foundation for the first attempts at VCA. The current state of VCA, with a special focus on facial and upper extremity transplantationUpper extremity transplant, will be explored, as will be issues of practical and ethical concern.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Revised Consent Model for the Transplantation of Face and Upper Limbs: Covenant ConsentVascularized Composite Allotransplantation

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Publisher
Springer International Publishing
Copyright
© Springer International Publishing AG 2017
ISBN
978-3-319-56399-2
Pages
9 –72
DOI
10.1007/978-3-319-56400-5_2
Publisher site
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Abstract

[In order to discuss the ethics of vascularized composite allotransplantation (VCA)Vascularized Composite Allotransplantation (VCA), it is necessary to have a firm grasp of this rapidly developing field, including its history, its present state and its anticipated future directions. The story of the development of VCA began in the imaginations of ancient peoples, but required important medical and surgical advances for the practice to become a reality. A survey of the history of VCAVascularized Composite Allotransplantation (VCA) will emphasize the role of advances in surgical techniques, including anastomosisAnastomosis of blood vessels and nerves and the emergence of microsurgeryMicrosurgery. It will also review the emergence of a better understanding of immunology and the development of effective means of immunosuppressionImmunosuppression. A brief survey of the beginnings of solid organ transplantationSolid Organ Transplantation (SOT) and limb replantationLimb replantation will be offered, as they together formed the technical foundation for the first attempts at VCA. The current state of VCA, with a special focus on facial and upper extremity transplantationUpper extremity transplant, will be explored, as will be issues of practical and ethical concern.]

Published: Apr 26, 2017

Keywords: Acute Rejection; Human Dignity; Chronic Rejection; Human Vulnerability; Composite Tissue

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