Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

A Systems Biology Approach to Study Metabolic SyndromeGut Microbiota in Metabolic Syndrome

A Systems Biology Approach to Study Metabolic Syndrome: Gut Microbiota in Metabolic Syndrome [The human gut is colonized by trillions of bacteria that complement our own human genes with 150-fold more microbial genes. Acting at the intersection between diet and host biology the gut microbiota can be considered a metabolic organ that affects host physiology. Here we explore evidence that supports the hypothesis that there is a dynamic interrelationship between our diet and gut microbiota that plays an important role in nutrition as well as modulating energy balance. Furthermore, the gut microbiota is altered in obesity and germ-free mice have reduced adiposity and are protected against diet-induced obesity. Accordingly, the gut microbiota may be considered an important environmental factor that contributes to obesity and metabolic diseases.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Systems Biology Approach to Study Metabolic SyndromeGut Microbiota in Metabolic Syndrome

Editors: Orešič, Matej; Vidal-Puig, Antonio
Bäckhed, Fredrik
A Systems Biology Approach to Study Metabolic Syndrome — Sep 25, 2013
Download PDF
11 pages

Loading next page...
 
/lp/springer-journals/a-systems-biology-approach-to-study-metabolic-syndrome-gut-microbiota-EOlK10c7CL
Publisher
Springer International Publishing
Copyright
© Springer International Publishing Switzerland 2014
ISBN
978-3-319-01007-6
Pages
171 –181
DOI
10.1007/978-3-319-01008-3_9
Publisher site
See Chapter on Publisher Site

Abstract

[The human gut is colonized by trillions of bacteria that complement our own human genes with 150-fold more microbial genes. Acting at the intersection between diet and host biology the gut microbiota can be considered a metabolic organ that affects host physiology. Here we explore evidence that supports the hypothesis that there is a dynamic interrelationship between our diet and gut microbiota that plays an important role in nutrition as well as modulating energy balance. Furthermore, the gut microbiota is altered in obesity and germ-free mice have reduced adiposity and are protected against diet-induced obesity. Accordingly, the gut microbiota may be considered an important environmental factor that contributes to obesity and metabolic diseases.]

Published: Sep 25, 2013

Keywords: Gut microbiota; Metabolism; Metagenome; Obesity

There are no references for this article.