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A Systems Biology Approach to Study Metabolic SyndromeLipid Metabolism in Metabolic Syndrome

A Systems Biology Approach to Study Metabolic Syndrome: Lipid Metabolism in Metabolic Syndrome [Lipoprotein metabolism is a complex system in which abnormal concentrations of various lipoprotein particles can result from alterations in their rates of production, conversion and/or catabolism. To develop novel strategies for the prevention and treatment of dyslipidaemia, it is essential to better understand the lipid disorders in humans. Here we discuss recent advances in the field as well as show how the use of tracers labeled with stable isotopes combined with mathematical modelling provides a powerful tool for probing lipid and lipoprotein kinetics in vivo; thus furthering our understanding of the pathogenesis of lipid disorders.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Systems Biology Approach to Study Metabolic SyndromeLipid Metabolism in Metabolic Syndrome

Editors: Orešič, Matej; Vidal-Puig, Antonio
Borén, Jan; Adiels, Martin
A Systems Biology Approach to Study Metabolic Syndrome — Sep 25, 2013
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Publisher
Springer International Publishing
Copyright
© Springer International Publishing Switzerland 2014
ISBN
978-3-319-01007-6
Pages
157 –170
DOI
10.1007/978-3-319-01008-3_8
Publisher site
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Abstract

[Lipoprotein metabolism is a complex system in which abnormal concentrations of various lipoprotein particles can result from alterations in their rates of production, conversion and/or catabolism. To develop novel strategies for the prevention and treatment of dyslipidaemia, it is essential to better understand the lipid disorders in humans. Here we discuss recent advances in the field as well as show how the use of tracers labeled with stable isotopes combined with mathematical modelling provides a powerful tool for probing lipid and lipoprotein kinetics in vivo; thus furthering our understanding of the pathogenesis of lipid disorders.]

Published: Sep 25, 2013

Keywords: Lipid metabolism; Liver; Tracer studies; Very low density lipopoprotein

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