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Abdominal SepsisClassification and Principals of Treatment

Abdominal Sepsis: Classification and Principals of Treatment [Intra-abdominal infection (IAI) is the second most common cause of severe sepsis in the intensive care unit (ICU). Even with optimal care, this disease process confers significant morbidity and mortality. The most common causes of IAI involve inflammation and perforation of the gastrointestinal tract including appendicitis, diverticulitis, and peptic ulcer disease. Other etiologies often more challenging to treat include postoperative complications, iatrogenic procedural complications, and traumatic injuries. Treatment is multimodal including, most importantly, source control in conjunction with timely systemic antimicrobial therapy, resuscitation, and supportive care. Given the wide spectrum of disease from focal isolated inflammation to diffuse peritonitis with septic shock and organ failure, the treatment is varied and complex. This chapter includes a review of clinical definitions and classification of the disease process as well as a basic overview of treatment.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Abdominal SepsisClassification and Principals of Treatment

Editors: Sartelli, Massimo; Bassetti, Matteo; Martin-Loeches, Ignacio
Abdominal Sepsis — Jun 23, 2017

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Publisher
Springer International Publishing
Copyright
© Springer International Publishing AG, part of Springer Nature 2018
ISBN
978-3-319-59703-4
Pages
1 –14
DOI
10.1007/978-3-319-59704-1_1
Publisher site
See Chapter on Publisher Site

Abstract

[Intra-abdominal infection (IAI) is the second most common cause of severe sepsis in the intensive care unit (ICU). Even with optimal care, this disease process confers significant morbidity and mortality. The most common causes of IAI involve inflammation and perforation of the gastrointestinal tract including appendicitis, diverticulitis, and peptic ulcer disease. Other etiologies often more challenging to treat include postoperative complications, iatrogenic procedural complications, and traumatic injuries. Treatment is multimodal including, most importantly, source control in conjunction with timely systemic antimicrobial therapy, resuscitation, and supportive care. Given the wide spectrum of disease from focal isolated inflammation to diffuse peritonitis with septic shock and organ failure, the treatment is varied and complex. This chapter includes a review of clinical definitions and classification of the disease process as well as a basic overview of treatment.]

Published: Jun 23, 2017

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