Abdominal Sepsis: Pyogenic Liver Abscess
Danson, Yeo; Yuan, Tan Ming; Shelat, Vishal G.
2017-06-23 00:00:00
[A hepatic abscess is a suppurated cavity caused by the invasion and multiplication of microorganisms within the liver parenchyma [1]. It can be bacterial (pyogenic), parasitic (amebic), mixed (pyogenic superinfection of parasitic abscess), or rarely fungal. Adult pyogenic liver abscess (PLA) is a major hepatobiliary infection with mortality of up to 46% [2–4]. The recent improvement in mortality can be attributed to improved understanding of sepsis with advances in interventional radiology and critical care. The cornerstone of PLA treatment remains antibiotic therapy with percutaneous drainage/aspiration. The first significant study on PLAs was performed by Ochsner in 1938, and he reported association with young men, portal pyemia, and 77% mortality [5].]
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[A hepatic abscess is a suppurated cavity caused by the invasion and multiplication of microorganisms within the liver parenchyma [1]. It can be bacterial (pyogenic), parasitic (amebic), mixed (pyogenic superinfection of parasitic abscess), or rarely fungal. Adult pyogenic liver abscess (PLA) is a major hepatobiliary infection with mortality of up to 46% [2–4]. The recent improvement in mortality can be attributed to improved understanding of sepsis with advances in interventional radiology and critical care. The cornerstone of PLA treatment remains antibiotic therapy with percutaneous drainage/aspiration. The first significant study on PLAs was performed by Ochsner in 1938, and he reported association with young men, portal pyemia, and 77% mortality [5].]
Published: Jun 23, 2017
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