Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Abdominal Solid Organ TransplantationInfection Complications After Abdominal Organ Transplantation

Abdominal Solid Organ Transplantation: Infection Complications After Abdominal Organ Transplantation [Infectious diseases are a leading complication after solid organ transplantation being associated with high morbidity and mortality. Patients undergoing abdominal organ transplantation have some unique risk factors for bacterial and fungal infections in the early phase (1 month) after transplantation. Hospital-acquired infections with multidrug-resistant pathogens are the main infectious threat in this period. From the 2nd to 6th month after transplantation, the risk of opportunistic infections is highest due to the high level of immunosuppression usually present at this time. Prevention strategies have reduced the incidence of viral, bacterial, fungal, and Pneumocystis diseases in this period. However, in some cases the incidence of such infections is only deferred to the late period, when prophylaxis is stopped. A lower index of suspicion and atypical manifestations of such infections in the late period (>6 months after SOT) may result in a delayed diagnosis and poor outcome. In the patients with uncomplicated clinical course and good graft function after transplantation, the risk of infection decreases in the late period becoming similar to that of general population. However, community-acquired infections may progress rapidly, and multiple pathogens (virus–bacteria, virus–fungi) may be present. Given the difficulties in diagnosis and management of infections in this setting, the prevention of infections is of paramount importance, and any effort to prevent infectious diseases should be done since the first patient assessment before transplantation. In this chapter the epidemiology, timing, management, and prevention of the main pathogens of infectious diseases after abdominal organ transplantation are reviewed.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Abdominal Solid Organ TransplantationInfection Complications After Abdominal Organ Transplantation

Editors: Pinna, Antonio Daniele; Ercolani, Giorgio
Giannella, Maddalena; Bartoletti, Michele; Viale, Pierluigi
Abdominal Solid Organ Transplantation — Mar 6, 2015
Download PDF
24 pages

Loading next page...
 
/lp/springer-journals/abdominal-solid-organ-transplantation-infection-complications-after-QLqw6S0mWF
Publisher
Springer International Publishing
Copyright
© Springer International Publishing Switzerland 2015
ISBN
978-3-319-16996-5
Pages
33 –56
DOI
10.1007/978-3-319-16997-2_2
Publisher site
See Chapter on Publisher Site

Abstract

[Infectious diseases are a leading complication after solid organ transplantation being associated with high morbidity and mortality. Patients undergoing abdominal organ transplantation have some unique risk factors for bacterial and fungal infections in the early phase (1 month) after transplantation. Hospital-acquired infections with multidrug-resistant pathogens are the main infectious threat in this period. From the 2nd to 6th month after transplantation, the risk of opportunistic infections is highest due to the high level of immunosuppression usually present at this time. Prevention strategies have reduced the incidence of viral, bacterial, fungal, and Pneumocystis diseases in this period. However, in some cases the incidence of such infections is only deferred to the late period, when prophylaxis is stopped. A lower index of suspicion and atypical manifestations of such infections in the late period (>6 months after SOT) may result in a delayed diagnosis and poor outcome. In the patients with uncomplicated clinical course and good graft function after transplantation, the risk of infection decreases in the late period becoming similar to that of general population. However, community-acquired infections may progress rapidly, and multiple pathogens (virus–bacteria, virus–fungi) may be present. Given the difficulties in diagnosis and management of infections in this setting, the prevention of infections is of paramount importance, and any effort to prevent infectious diseases should be done since the first patient assessment before transplantation. In this chapter the epidemiology, timing, management, and prevention of the main pathogens of infectious diseases after abdominal organ transplantation are reviewed.]

Published: Mar 6, 2015

Keywords: Abdominal organ transplant recipients; Bacterial infection; Viral infection; Fungal infection; Classification of infections after solid organ transplantation; Prevention of infections in abdominal organt transplant patients

There are no references for this article.