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Characterization of catechins, theaflavins, and flavonols by leaf processing step in green and black teas (Camellia sinensis) using UPLC-DAD-QToF/MSEuropean Food Research and Technology, 245
Mengchun Chen, Xiaoqian Zhang, Hao Wang, Baoli Lin, Shuanghu Wang, G. Hu (2015)
Determination of rutin in rat plasma by ultra performance liquid chromatography tandem mass spectrometry and application to pharmacokinetic study.Journal of chromatographic science, 53 4
K. Monks, H. Rieger, I. Molnár (2011)
Expanding the term "Design Space" in high performance liquid chromatography (I).Journal of pharmaceutical and biomedical analysis, 56 5
R. Kayesh, Md. Jahan, Md. Sultan (2017)
Development Using Response Surface Methodology and Validation of a Stability-Indicating RP-HPLC Method for Simultaneous Estimation of Azilsartan Medoxomil and Chlorthalidone in Solid Dosage FormChromatographia, 80
M. Roman (2013)
Determination of catechins and caffeine in camillia sinensis raw materials, extracts, and dietary supplements by HPLC-uv: single-laboratory validation.Journal of AOAC International, 96 5
(2015)
Inter - national council for harmonization of technical requirements for pharmaceuticals for human use , ICH guideline Q 9 on quality risk management
S. Rahman, Oly Katari, Datta Pawde, Gopi Boddeda, A. Goswami, S. Mutheneni, T. Shunmugaperumal (2021)
Application of Design of Experiments® Approach-Driven Artificial Intelligence and Machine Learning for Systematic Optimization of Reverse Phase High Performance Liquid Chromatography Method to Analyze Simultaneously Two Drugs (Cyclosporin A and Etodolac) in Solution, Human Plasma, Nanocapsules, andAAPS PharmSciTech, 22 4
R. Kayesh, Md. Sultan (2015)
A novel ion-pair RP-HPLC method for simultaneous quantification of naproxen and esomeprazole in pharmaceutical formulations.Journal of chromatographic science, 53 5
P.K. Sahu, N.R. Ramisetti, T. Cecchi, S. Swain, C.S. Patro, J. Panda (2018)
10.1016/J.JPBA.2017.05.006J. Pharm. Biomed. Anal., 147
Andrija Ćirić, Nevena Ivanović, M. Cvijović, M. Jelikiċ-Stankov, Ljubinka Joksović, P. Djurdjević (2014)
Chemometric-Assisted Optimization of RP-HPLC Method for Determination of Some Bioflavonoids in Brassica oleracea Species and Their Antioxidative ActivityFood Analytical Methods, 7
A. Rana, E. Sharma, K. Rawat, Ranjana Sharma, S. Verma, Y. Padwad, A. Gulati (2016)
Screening and purification of catechins from underutilized tea plant parts and their bioactivity studiesJournal of Food Science and Technology, 53
P. Naveen, H.B. Lingaraju, K.S. Prasad (2017)
10.4103/jphi.JPHI_33_17Int. J. Pharm. Invest., 7
I. Molnár, H. Rieger, K. Monks (2010)
Aspects of the "Design Space" in high pressure liquid chromatography method development.Journal of chromatography. A, 1217 19
Ming-Hua Hao, Fan Zhang, Xing-Xia Liu, Li-Juan Wang, Sai-Juan Xu, Jin-Hua Zhang, H. Ji, Ping Xu (2018)
Qualitative and quantitative analysis of catechin and quercetin in flavonoids extracted from Rosa roxburghii TrattTropical journal of pharmaceutical research : TJPR, 17
Yang Huang, Guangyun Tang, Tingting Zhang, M. Fillet, J. Crommen, Zhengjin Jiang (2018)
Supercritical fluid chromatography in traditional Chinese medicine analysisJournal of Pharmaceutical and Biomedical Analysis, 147
Raju Gottumukkala, Nareshraju Nadimpalli, Kannababu Sukala, G. Subbaraju (2014)
Determination of Catechin and Epicatechin Content in Chocolates by High-Performance Liquid ChromatographyInternational Scholarly Research Notices, 2014
J. Pandey, T. Bastola, Julu Tripathi, Milu Tripathi, R. Rokaya, Bhawana Dhakal, Rabin C., R. Bhandari, A. Poudel (2020)
Estimation of Total Quercetin and Rutin Content in Malus domestica of Nepalese Origin by HPLC Method and Determination of Their Antioxidative ActivityJournal of Food Quality, 2020
V. Kuntić, N. Pejić, B. Ivković, Z. Vujić, K. Ilić, S. Mićić, V. Vukojević (2007)
Isocratic RP-HPLC method for rutin determination in solid oral dosage forms.Journal of pharmaceutical and biomedical analysis, 43 2
B. Jayagopal, M. Shivashankar (2017)
10.2412/mmse.96.97.276Mech. Mater. Sci. Eng. J., 9
S. Karmarkar, R. Garber, Y. Genchanok, S. George, X. Yang, R. Hammond (2011)
Quality by design (QbD) based development of a stability indicating HPLC method for drug and impurities.Journal of chromatographic science, 49 6
R. Kayesh (2017)
9395023J. Chem., 2017
S. Emilia, R.D. Yetti, R. Asra (2020)
GaloreInt. J. Health Sci. Res, 5
M.K. Kim, S.C. Park, G. Park, E. Choi, Y. Ji, Y.P. Jang (2021)
10.1038/S41598-021-91341-WSci. Rep., 11
Yanqiong Wang, Shuyi Li, Dandan Han, Kehan Meng, Miao Wang, Chunjie Zhao (2015)
Simultaneous Determination of Rutin, Luteolin, Quercetin, and Betulinic Acid in the Extract of Disporopsis pernyi (Hua) Diels by UPLCJournal of Analytical Methods in Chemistry, 2015
S. Wangkarn, K. Grudpan, C. Khanongnuch, Thanawat Pattananandecha, Sutasinee Apichai, C. Saenjum (2021)
Development of HPLC Method for Catechins and Related Compounds Determination and Standardization in Miang (Traditional Lanna Fermented Tea Leaf in Northern Thailand)Molecules, 26
The current study highlights the systematic quality by design assisted creation of an efficient analytical technique for the estimation of rutin and catechin in corn silk extract tablets. Quercetin was considered as an internal standard. Response surface methodology in the design of experiments was used for identifying key material attributes and critical process parameters that influence the designated critical analytical attributes. Separation was achieved on the HSS C18 column (100 × 2.1 mm, 1.8 μm). The effects of acetonitrile content (v/v), flow rate, and column temperature on the retention times of the two drugs and their resolution and the number of theoretical plates were investigated and optimized. The optimum chromatographic conditions within the design space were found to be an isocratic mobile phase consisting of buffer and acetonitrile (61.5 : 38.5, v/v) with a flow rate of 0.29 mL/min and a run time of 4 min. The retention times of rutin and catechin were found to be 1.9 and 2.8 min. Different validation parameters were established, and the approach was validated in agreement with the ICH and FDA requirements. Data analysis using statistical methods has revealed that the method is reliable, accurate, and robust.
Journal of Analytical Chemistry – Springer Journals
Published: May 1, 2023
Keywords: response surface methodology; design of experiments; central composite design; critical analytical attributes; Design-Expert 10.0.2 software
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