Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Doumeng, L. Makhlouf, F. Berthet, O. Marsan, Karl Delbé, J. Denape, F. Chabert (2021)
A comparative study of the crystallinity of polyetheretherketone by using density, DSC, XRD, and Raman spectroscopy techniquesPolymer Testing
E. Vranić, A. Mehmedagić, S. Hadžović (2002)
Mathematical methods for quantification and comparison of dissolution testing data.Bosnian journal of basic medical sciences, 2 1-2
M. Godbole, P. Sabale, V. Mathur (2020)
Development of lamivudine liposomes by three-level factorial design approach for optimum entrapment and enhancing tissue targetingJournal of Microencapsulation, 37
Qing-Ri Cao, Yan Liu, Wei-Juan Xu, Beom-Jin Lee, Mingshi Yang, J. Cui (2012)
Enhanced oral bioavailability of novel mucoadhesive pellets containing valsartan prepared by a dry powder-coating technique.International journal of pharmaceutics, 434 1-2
S. Biswal, J. Sahoo, P. Murthy, R. Giradkar, J. Avari (2008)
Enhancement of Dissolution Rate of Gliclazide Using Solid Dispersions with Polyethylene Glycol 6000AAPS PharmSciTech, 9
V. Mohit, Garse Harshal, Dand Neha, Kadam Vilasrao, H. Rajashree (2011)
A comparative study of complexation methods for cefdinir-hydroxypropyl-β-cyclodextrin systemJournal of Inclusion Phenomena and Macrocyclic Chemistry, 71
Carlos Jensen, R. Santos, Â. Denadai, C. Santos, A. Braga, R. Sinisterra (2010)
Pharmaceutical Composition of Valsartan: β-Cyclodextrin: Physico–Chemical and Characterization Anti-Hypertensive EvaluationMolecules, 15
A. Zaid, A. Qaddomi, Mashhour Ghanem, Lina Shehadeh, M. Abualhasan, S. Natur, S. Khammash (2015)
Development of a Dissolution Method to Compare Tablet Formulations Containing Valsartan/AmlodipineDissolution Technologies, 22
Kiyota Sakai, Yukihide Sato, M. Okada, S. Yamaguchi (2022)
Cyclodextrins produced by cyclodextrin glucanotransferase mask beany off-flavors in plant-based meat analogsPLoS ONE, 17
Jianyi Wang, Xiangfu Jiang, Zebin Guo, Baodong Zheng, Yi Zhang (2021)
Insights into the multi-scale structural properties and digestibility of lotus seed starch-chlorogenic acid complexes prepared by microwave irradiation.Food chemistry, 361
B. Nalluri, Ramya Krishna, Rao, Peter Crooks (2012)
Effect of Recrystallization on the Pharmaceutical Properties of Valsartan for Improved Therapeutic Efficacyjournal of applied pharmaceutical science
Saikishore Meruva, Prajwal Thool, Shawreen Shah, S. Karki, W. Bowen, I. Ghosh, Sumit Kumar (2019)
Formulation and performance of Irbesartan nanocrystalline suspension and granulated or bead-layered dried powders - Part I.International journal of pharmaceutics
A. Ghosh, S. Biswas, T. Ghosh (2011)
Preparation and Evaluation of Silymarin β-cyclodextrin Molecular Inclusion ComplexesJournal of Young Pharmacists : JYP, 3
M. Cirri, F. Maestrelli, N. Mennini, P. Mura (2009)
Physical-chemical characterization of binary and ternary systems of ketoprofen with cyclodextrins and phospholipids.Journal of pharmaceutical and biomedical analysis, 50 5
Zunaira Alvi, Muhammad Akhtar, A. Mahmood, N. ur-Rahman, Imran Nazir, Hadia Sadaquat, Muhammad Ijaz, S. Syed, M. Waqas, Yi Wang (2021)
Enhanced Oral Bioavailability of Epalrestat SBE7-β-CD Complex Loaded Chitosan Nanoparticles: Preparation, Characterization and in-vivo Pharmacokinetic EvaluationInternational Journal of Nanomedicine, 16
Srivalli Valipe (2015)
Scanning Electron Microscopy (SEM)
(2018)
Infrared spectral interpretation. 2018
Sheng Fang, Xinling Peng, Xianrui Liang, Jianli Shen, Jian Wang, Jie Chen, Yue-cheng Meng (2019)
Enhancing Water Solubility and Stability of Natamycin by Molecular Encapsulation in Methyl-β-Cyclodextrin and its Mechanisms by Molecular Dynamics SimulationsFood Biophysics, 15
C. Ratti (2001)
Hot air and freeze-drying of high-value foods : a reviewJournal of Food Engineering, 49
Naumana Rabbani, P. Seville (2005)
The influence of formulation components on the aerosolisation properties of spray-dried powders.Journal of controlled release : official journal of the Controlled Release Society, 110 1
Subhraseema Das, Subhrajit Mohanty, Jitendra Maharana, S. Jena, Jasmine Nayak, U. Subuddhi (2020)
Microwave-assisted β-cyclodextrin/chrysin inclusion complexation: An economical and green strategy for enhanced hemocompatibility and chemosensitivity in vitroJournal of Molecular Liquids, 310
Y. Yan, J. Sung, Kun Kim, Dong Kim, Jong Kim, Beom-Jin Lee, C. Yong, Han‐Gon Choi (2012)
Novel valsartan-loaded solid dispersion with enhanced bioavailability and no crystalline changes.International journal of pharmaceutics, 422 1-2
F. Lagrange (2010)
Developing solid oral dosage forms: pharmaceutical theory and practice, Y. Qiu, Y. Chen, G.G.Z. Zhang, L. Liu, W. Porter. Elsevier (2009). 978 pp., 155 €, ISBN: 978-0-444-53242-8Le Pharmacien Hospitalier, 45
R. Challa, A. Ahuja, J. Ali, R. Khar (2005)
Cyclodextrins in drug delivery: An updated reviewAAPS PharmSciTech, 6
Cindy Enggi, Mega Satria, Nirmayanti Nirmayanti, Jesscia Usman, Julika Nur, R. Asri, N. Djide, A. Permana (2022)
Improved transdermal delivery of valsartan using combinatorial approach of polymeric transdermal hydrogels and solid microneedles: an ex vivo proof of concept investigationJournal of Biomaterials Science, Polymer Edition, 34
J. Valente, J. Dias, Â. Sousa, N. Alves (2019)
Composite Central Face Design—An Approach to Achieve Efficient Alginate MicrocarriersPolymers, 11
Eda Gülmezoğlu, Gülbeyaz Türkyılmaz, H. Karasulu (2022)
Preparation and evaluation of a lipid-based drug delivery system to ımprove valsartan oral bioavailability: pharmacokinetic and pharmacodynamic analysisDrug Development and Industrial Pharmacy, 48
Wei-Juan Xu, Hongjuan Xie, Qing-Ri Cao, Liao Shi, Yue Cao, Xiao-Yin Zhu, J. Cui (2016)
Enhanced dissolution and oral bioavailability of valsartan solid dispersions prepared by a freeze-drying technique using hydrophilic polymersDrug Delivery, 23
Shantanu Bandopadhyay, S. Beg, O. Katare, Teenu Sharma, Bhupinder Singh (2020)
Integrated Analytical Quality by Design (AQbD) Approach for the Development and Validation of Bioanalytical Liquid Chromatography Method for Estimation of Valsartan.Journal of chromatographic science, 58 7
S. Beg, S. Swain, H. Singh, C. Patra, M. Rao (2012)
Development, Optimization, and Characterization of Solid Self-Nanoemulsifying Drug Delivery Systems of Valsartan Using Porous CarriersAAPS PharmSciTech, 13
Victoria Yan, F. Muller (2020)
Captisol and GS-704277, but Not GS-441524, Are Credible Mediators of Remdesivir’s NephrotoxicityAntimicrobial Agents and Chemotherapy, 64
N. Siddiqui, A. Husain, L. Chaudhry, M. Alam, Moloy Mitra, P. Bhasin (2011)
Pharmacological and Pharmaceutical Profile of Valsartan: A Review
A. Nasr, Fayrouz Moftah, Mohammed Abourehab, S. Gad (2022)
Design, Formulation, and Characterization of Valsartan Nanoethosomes for Improving Their BioavailabilityPharmaceutics, 14
D. Shin, B. Chae, Y. Goo, H. Yoon, C. Kim, S. Sohn, Dongho Oh, Ahram Lee, S. Song, Y. Choi (2019)
Improved Dissolution and Oral Bioavailability of Valsartan Using a Solidified Supersaturable Self-Microemulsifying Drug Delivery System Containing Gelucire® 44/14Pharmaceutics, 11
B. Cappello, C. Maio, M. Iervolino, A. Miro (2006)
Improvement of Solubility and Stability of Valsartan by Hydroxypropyl-\boldbeta-CyclodextrinJournal of inclusion phenomena and macrocyclic chemistry, 54
T. Higuchi, A. Connors (1965)
Phase solubility techniques, 4
M. Moneghini, B. Bellich, P. Baxa, F. Princivalle (2008)
Microwave generated solid dispersions containing Ibuprofen.International journal of pharmaceutics, 361 1-2
C Ni, QJ Wang, Y-W Chung (2013)
Scanning Electron Microscopy (SEM)Encyclopedia of Tribology
Anroop Nair, Shery Jacob (2016)
A simple practice guide for dose conversion between animals and humanJournal of Basic and Clinical Pharmacy, 7
N. Ahmad, R. Ahmad, A. Al-Qudaihi, Salman Alaseel, Ibrahim Fita, M. Khalid, F. Pottoo (2019)
Preparation of a novel curcumin nanoemulsion by ultrasonication and its comparative effects in wound healing and the treatment of inflammationRSC Advances, 9
Rabab Husseiny, A. Lila, M. Abdallah, H. El-ghamry (2018)
Fast disintegrating tablet of Valsartan for the treatment of pediatric hypertension: In vitro and in vivo evaluationJournal of Drug Delivery Science and Technology, 43
A. Gelman (2005)
Discussion of "Analysis of variance--why it is more important than ever" by A. GelmanarXiv: Statistics Theory
Lisa Ryno, Yael Levine, P. Iovine (2014)
Synthesis, characterization, and comparative analysis of amylose-guest complexes prepared by microwave irradiation.Carbohydrate research, 383
Yong Zhang, Meirong Huo, Jianping Zhou, Shaofei Xie (2010)
PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft ExcelComputer methods and programs in biomedicine, 99 3
N. Ranpise, N. Kulkarni, Parth Mair, A. Ranade (2009)
Improvement of water solubility and in vitro dissolution rate of aceclofenac by complexation with β-cyclodextrin and hydroxypropyl-β-cyclodextrinPharmaceutical Development and Technology, 15
N. Koseki, Hiroto Kawashita, Hisanori Hara, M. Niina, Makoto Tanaka, R. Kawai, Y. Nagae, N. Masuda (2007)
Development and validation of a method for quantitative determination of valsartan in human plasma by liquid chromatography-tandem mass spectrometry.Journal of pharmaceutical and biomedical analysis, 43 5
Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
Nadeem Siddiqui (2011)
12J Appl Pharm Sci, 01
The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan. Phase solubility investigations showed an AL type curve. The estimated apparent stability constant for valsartan SBE7-β-CD is 427 ± 0.32 M−1. Inclusion complexes of valsartan SBE7-β-CD in equal molar ratio were prepared by microwave irradiation technique. The process parameters were optimised with a central composite face design. Response surface graphs and contour plots showed how process factors affected drug content. The inclusion complexes prepared by optimising process variables are characterised. The DSC and X-ray diffraction confirm the formation of inclusion complexes and the drug’s transition from a crystalline to an amorphous state. FTIR suggests hydrogen bonding between valsartan and SBE7-β-CD. SEM showed changes in drug morphology and shape. The dissolution rate of the prepared SBE7-β-CD complex using microwave irradiation was 2.85 times that of pure valsartan. The inclusion complex was formulated into tablet dosage forms F1 to F4. Furthermore, oral bioavailability studies in rats with tablet formulation F3 were carried out and compared to the marketed Diovan® tablet as a reference standard. The F3 tablet formulation exhibited significantly higher values of AUC0-∞ and Cmax than the reference. Finally, the microwave-irradiated valsartan SBE7-β-CD inclusion complex converted into tablet dosage form may be a promising approach to increasing valsartan oral bioavailability.
AAPS PharmSciTech – Springer Journals
Published: May 9, 2023
Keywords: Microwave-irradiated inclusion complexes; Modified β-cyclodextrin; Response surface methodology; SBE7-β-CD; Valsartan
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.