Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Recombinant Glycoprotein ProductionPlatforms for Recombinant Therapeutic Glycoprotein Production

Recombinant Glycoprotein Production: Platforms for Recombinant Therapeutic Glycoprotein Production [The majority of FDA-approved biology-derived products are recombinant glycoproteins. These proteins have been used for the treatment of several diseases, with numerous products currently approved for clinical use. The choice of the expression system is a key step toward a successful functional protein production, since glycosylation influences yield, pharmacokinetics, biological activity, and immunogenicity. This chapter covers the general aspects of therapeutic recombinant glycoproteins and the platforms that are being employed for their production.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Recombinant Glycoprotein ProductionPlatforms for Recombinant Therapeutic Glycoprotein Production

Part of the Methods in Molecular Biology Book Series (volume 1674)
Editors: Picanço-Castro, Virgínia; Swiech, Kamilla

Loading next page...
 
/lp/springer-journals/recombinant-glycoprotein-production-platforms-for-recombinant-KaQ3RcCPNd

References (60)

Publisher
Springer New York
Copyright
© Springer Science+Business Media LLC 2018
ISBN
978-1-4939-7311-8
Pages
1 –14
DOI
10.1007/978-1-4939-7312-5_1
Publisher site
See Chapter on Publisher Site

Abstract

[The majority of FDA-approved biology-derived products are recombinant glycoproteins. These proteins have been used for the treatment of several diseases, with numerous products currently approved for clinical use. The choice of the expression system is a key step toward a successful functional protein production, since glycosylation influences yield, pharmacokinetics, biological activity, and immunogenicity. This chapter covers the general aspects of therapeutic recombinant glycoproteins and the platforms that are being employed for their production.]

Published: Sep 19, 2017

Keywords: Recombinant glycoprotein; Glycosylation; Expression systems; Mammalian cells; Human cells; Insect cells; Plant cells; Bacteria; Yeasts

There are no references for this article.