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- Publisher
- Springer Journals
- Copyright
- Copyright © 1999 by Human Sciences Press, Inc.
- Subject
- Medicine & Public Health; Public Health
- ISSN
- 0894-5888
- eISSN
- 1573-9767
- DOI
- 10.1023/B:JAME.0000008703.34341.9e
- Publisher site
- See Article on Publisher Site
Abstract
The aging of the nervous system is not fully understood, but defects in mitochondrial energy production, originating in mitochondrial DNA mutations, have been implicated, along with neurotransmitter deficiencies and excitotoxic mechanisms. Molecules involved in energy metabolism, such as NADH, acetyl-L-carnitine, ubiquinone, and lipoic acid, are potentially therapeutic. Various natural and synthetic Pharmaceuticals can retard senility by influencing neurotransmitters, modulating NMDA-receptor mechanisms, enhancing circulation and metabolism, acting as antioxidants, and in other ways. Certain Pharmaceuticals, including meclofenoxate, ergoloid mesylates, piracetam, ginkgo, and vinpocetine, have plural effects in the nervous system.
Journal
Journal of Advancement in Medicine – Springer Journals
Published: Sep 30, 2004