Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Systems Biology in Biotech & PharmaIntegrative Systems Biology II—Molecular Biology: Phase 2 Lead Discovery and In Silico Screening

Systems Biology in Biotech & Pharma: Integrative Systems Biology II—Molecular Biology: Phase 2... [Many different OMICs/HTS techniques now allow huge amounts of molecular signatures to be collected and then analysed further by system tools. Among them, ChIP-on-chip is used to investigate interactions between proteins and DNA in vivo. Chemogenomics, morphogenics and synthetic biology are only in the early stages of development, but may contribute to target identification. A key SB tool, the reconstruction of biological networks, represents an emerging field, undergoing explosive expansion, and will likely enable efficient mapping of gene onto function.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Systems Biology in Biotech & PharmaIntegrative Systems Biology II—Molecular Biology: Phase 2 Lead Discovery and In Silico Screening

Loading next page...
 
/lp/springer-journals/systems-biology-in-biotech-pharma-integrative-systems-biology-ii-V4z02h6OYc

References (35)

Publisher
Springer Netherlands
Copyright
© The Author(s) 2012
ISBN
978-94-007-2848-6
Pages
39 –49
DOI
10.1007/978-94-007-2849-3_4
Publisher site
See Chapter on Publisher Site

Abstract

[Many different OMICs/HTS techniques now allow huge amounts of molecular signatures to be collected and then analysed further by system tools. Among them, ChIP-on-chip is used to investigate interactions between proteins and DNA in vivo. Chemogenomics, morphogenics and synthetic biology are only in the early stages of development, but may contribute to target identification. A key SB tool, the reconstruction of biological networks, represents an emerging field, undergoing explosive expansion, and will likely enable efficient mapping of gene onto function.]

Published: Jan 4, 2012

Keywords: Synthetic Biology; High Throughput Screening; Flux Balance Analysis; Network Reconstruction; Ontology Building

There are no references for this article.