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The Art of Carbohydrate AnalysisAnalysis of Carbohydrates by Mass SpectrometryMass spectrometry (MS)

The Art of Carbohydrate Analysis: Analysis of Carbohydrates by Mass SpectrometryMass spectrometry... [Mass spectrometry has become the favorite technique for glycomics analysis. This chapter describes the different ionization methods and provides examples of application, with comprehensive literature references. Mass fragmentation of monosaccharide and oligosaccharide derivatives will be discussed. The glycan compositions are usually determined based on accurate masses and tandem mass spectrometry. The coupling of modern separation techniques directly to the mass spectrometer, together with automated tools for interpretation of the MS data using database searching, are common techniques nowadays.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

The Art of Carbohydrate AnalysisAnalysis of Carbohydrates by Mass SpectrometryMass spectrometry (MS)

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References (67)

Publisher
Springer International Publishing
Copyright
© Springer Nature Switzerland AG 2021
ISBN
978-3-030-77790-6
Pages
253 –271
DOI
10.1007/978-3-030-77791-3_11
Publisher site
See Chapter on Publisher Site

Abstract

[Mass spectrometry has become the favorite technique for glycomics analysis. This chapter describes the different ionization methods and provides examples of application, with comprehensive literature references. Mass fragmentation of monosaccharide and oligosaccharide derivatives will be discussed. The glycan compositions are usually determined based on accurate masses and tandem mass spectrometry. The coupling of modern separation techniques directly to the mass spectrometer, together with automated tools for interpretation of the MS data using database searching, are common techniques nowadays.]

Published: Oct 24, 2021

Keywords: HPLC-MS; GC-MS; EI-MS; ESI-MS; MALDI-TOF-MS; DHB; ATT; THAP; IgG; N-glycans; O-glycans; Permethylation; CID-MS; MS/MS

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