Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Utilizzo dei fattori di crescita nelle lesioni del tendine rotuleo

Utilizzo dei fattori di crescita nelle lesioni del tendine rotuleo Chronic tendinopathies represent one of the most common causes of longterm pain and physical disability. Because of poor tendon vascularity and because of the istopathologic changes in the damaged area, tendon healing rate is relatively low compared with other connective tissues, inducing a poor clinical and functional outcome. For these reasons, beside classic surgical and conservative treatments, new therapeutic approaches, such as the use of growth factors, were developed in order to enhance biologic response and healing processes. One of the most innovative systems is based on PRP. PRP (Platelet-Rich Plasma) is a plasma layer, separated after centrifugation of an autologous blood sample, in which platelets are about 8 times more concentrated than in normal plasma. The rationale of this technique is based on scientific evidence of the importance of growth factors, contained in platelet granules, in the normal tendon healing process. In this article we report the effects on clinical, functional and instrumental outcomes of US-guided injections of autologous PRP in 20 patients with patellar tendinopathy, aged between 18 and 43 years, treated in our clinic between 2010 and 2013. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archivio di Ortopedia e Reumatologia Springer Journals

Utilizzo dei fattori di crescita nelle lesioni del tendine rotuleo

Download PDF
3 pages

Loading next page...
 
/lp/springer-journals/utilizzo-dei-fattori-di-crescita-nelle-lesioni-del-tendine-rotuleo-OOB5s0AThB
Publisher
Springer Journals
Copyright
Copyright © 2013 by Springer-Verlag Italia
Subject
Medicine & Public Health; Orthopedics
ISSN
0390-7368
eISSN
1592-7113
DOI
10.1007/s10261-013-0045-2
Publisher site
See Article on Publisher Site

Abstract

Chronic tendinopathies represent one of the most common causes of longterm pain and physical disability. Because of poor tendon vascularity and because of the istopathologic changes in the damaged area, tendon healing rate is relatively low compared with other connective tissues, inducing a poor clinical and functional outcome. For these reasons, beside classic surgical and conservative treatments, new therapeutic approaches, such as the use of growth factors, were developed in order to enhance biologic response and healing processes. One of the most innovative systems is based on PRP. PRP (Platelet-Rich Plasma) is a plasma layer, separated after centrifugation of an autologous blood sample, in which platelets are about 8 times more concentrated than in normal plasma. The rationale of this technique is based on scientific evidence of the importance of growth factors, contained in platelet granules, in the normal tendon healing process. In this article we report the effects on clinical, functional and instrumental outcomes of US-guided injections of autologous PRP in 20 patients with patellar tendinopathy, aged between 18 and 43 years, treated in our clinic between 2010 and 2013.

Journal

Archivio di Ortopedia e Reumatologia – Springer Journals

Published: Jan 10, 2014

References

  • Platelet rich placebo?
    Hall, MP; Ward, JP; Cardone, DA
  • Achilles tendon disorders: etiology and epidemiology
    Järvinen, TA; Kannus, P; Maffulli, N; Khan, KM
  • Engineering of functional tendon
    Calve, S; Dennis, RG; Kosnik, PE
  • Functional efficacy of tendon repair processes
    Butler, DL; Juncosa, N; Dressler, MR
  • Tendon: biology, biomechanics, repair, growth factors, and evolving treatment options
    James, R; Kesturu, G; Balian, G; Chhabra, AB
  • Etiology and pathophysiology of tendon ruptures in sports
    Kannus, P; Natri, A
  • Prevalence of jumper’s knee among elite athletes from different sports: a cross-sectional study
    Lian, OB; Engebretsen, L; Bahr, R
  • The role of paratenon in healing of experimental tendon transplants
    Schneewind, JH; Kline, IK; Monsour, CW
  • Fundamental aspects of wound healing relating to the restoration of gliding function after tendon repair
    Peacock, EE
  • Maintenance of the gliding surface of tendon autografts in dogs
    Abrahamsson, SO; Gelberman, R
  • The fibroblast in flexor tendon healing
    Lindsay, WK; Birch, JR
  • Vascularization of the healing wound
    Myers, B; Wolf, M
  • Identification of the collagen-producing cells in healing flexor tendons
    Garner, WL; McDonald, JA; Koo, M
  • The vasculature and its role in the damaged and healing tendon
    Fenwick, SA; Hazleman, BL; Riley, GP
  • Collagen in tendon, ligament, and bone healing. A current review
    Liu, SH; Yang, RS; al-Shaikh, R; Lane, JM
  • Tissue engineered biological augmentation for tendon healing: a systematic review
    Longo, UG; Lamberti, A; Maffulli, N; Denaro, V
  • Light microscopic histology of achilles tendon ruptures. A comparison with unruptured tendons
    Maffulli, N; Barrass, V; Ewen, SW
  • Current treatment options for tendinopathy
    Maffulli, N; Longo, UG; Loppini, M; Denaro, V
  • Free hamstrings tendon transfer and interference screw fixation for less invasive reconstruction of chronic avulsions of the Achilles tendon
    Maffulli, N; Longo, UG; Spiezia, F; Denaro, V
  • VISA-P score for patellar tendinopathy in males: adaptation to Italian
    Maffulli, N; Longo, UG; Testa, V
  • Growth factor delivery methods in the management of sports injuries: the state of play
    Creaney, L; Hamilton, B
  • Current opinion about using the platelet-rich gel in orthopaedics and trauma surgery
    Wrotniak, M; Bielecki, T; Gadzik, TS
  • Reconstruction of chronic patellar tendon rupture with contralateral BTB autograft: a case report
    Milankov, MZ; Miljkovic, N; Stankovic, M
  • Chronic patellar tendon rupture reconstruction with a semitendinosus autograft
    Nguene-Nyemb, AG; Huten, D; Ropars, M
  • Disruption of the extensor mechanism of the knee
    McGrory, JE
  • Ruptures of the extensor mechanism of the knee joint
    Siwek, CW; Rao, JP
  • Long-term prognosis for jumper’s knee in male athletes
    Kettunen, JA; Kvist, M; Alanen, E; Kujala, UM
  • Achilles and patellar tendinopathy: current understanding of pathophysiology and management
    Tan, SC; Chan, O
  • Ultrasound-guided injection of platelet-rich plasma in chronic Achilles and patellar tendinopathy
    Ferrero, G; Fabbro, E; Orlandi, D
  • Eccentric decline squat protocol offers superior results at 12 months compared with traditional eccentric protocol for patellar tendinopathy in volleyball players
    Young, MA; Cook, JL; Purdam, CR
  • Ultrasonography as a tool for diagnosis, guidance of local steroid injection and, together with pressure algometry, monitoring of the treatment of athletes with chronic jumper’s knee and Achilles tendinitis: a randomized, double-blind, placebo-controlled study
    Fredberg, U; Bolvig, L; Pfeiffer-Jensen, M
  • An overview of shock wave therapy in musculoskeletal disorders
    Wang, CJ
  • Surgical treatment for chronic Achilles tendinopathy: a prospective seven month follow up study
    Paavola, M; Kannus, P; Orava, S
  • Surgical treatment of patellar tendon pain in athletes
    Orava, S; Osterback, L; Hurme, M
  • Use of platelet-rich plasma to enhance tendon function and cellularity
    Lane, JG; Healey, RM; Chase, DC; Amiel, D
  • Platelet-rich plasma application in the management of chronic tendinopathies
    Kaux, JF; Crielaard, JM
  • New insights into and novel applications for platelet-rich fibrin therapies
    Anitua, E; Sánchez, M; Nurden, AT
  • Is platelet-rich plasma the perfect enhancement factor? A current review
    Sánchez, AR; Sheridan, PJ; Kupp, LI
  • Platelet-rich plasma: evidence to support its use
    Marx, RE
  • Dental and craniofacial applications of platelet-rich plasma
    RE, M; AK, G
  • Comparison of surgically repaired Achilles tendon tears using platelet-rich fibrin matrices
    Sánchez, M; Anitua, E; Azofra, J
  • Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing
    Eppley, BL; Woodell, JE; Higgins, J
  • Inflammatory cell response to acute muscle injury
    Tidball, JG
  • Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems
    Castillo, TN; Pouliot, MA; Kim, HJ; Dragoo, JL
  • Platelet-rich plasma: new clinical application: a pilot study for treatment of jumper’s knee
    Kon, E; Filardo, G; Delcogliano, M