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S. Tardito, A. Barilli, I. Bassanetti, M. Tegoni, O. Bussolati, R. Franchi‐Gazzola, C. Mucchino, L. Marchiò (2012)
Copper-dependent cytotoxicity of 8-hydroxyquinoline derivatives correlates with their hydrophobicity and does not require caspase activation.Journal of medicinal chemistry, 55 23
K. Nomiya, Kiyoshi Sekino, Motoki Ishikawa, A. Honda, M. Yokoyama, Noriko Kasuga, H. Yokoyama, Saori Nakano, K. Onodera (2004)
Syntheses, crystal structures and antimicrobial activities of monomeric 8-coordinate, and dimeric and monomeric 7-coordinate bismuth(III) complexes with tridentate and pentadentate thiosemicarbazones and pentadentate semicarbazone ligands.Journal of inorganic biochemistry, 98 4
Kirralee Burke, Liam Stephens, Melissa Werrett, P. Andrews (2020)
Bismuth(III) flavonolates: the impact of structural diversity on antibacterial activity, mammalian cell viability, and cellular uptake.Chemistry
I. Marzano, M. Franco, Priscila Silva, R. Augusti, G. Santos, N. Fernandes, M. Bucciarelli-Rodriguez, E. Chartone‐Souza, E. Pereira-Maia (2013)
Crystal Structure, Antibacterial and Cytotoxic Activities of a New Complex of Bismuth(III) with SulfapyridineMolecules, 18
L. Opris, Anca Silvestru, C. Silvestru, H. Breunig, E. Lork (2003)
Solid-state structure and solution behaviour of hypervalent organoantimony halides containing 2-(Me2NCH2)C6H4- moietiesDalton Transactions
Marcela López-Cardoso, Hugo Tlahuext, Marco Pérez-Salgado, D. Vargas-Pineda, Perla Román-Bravo, A. Cotero-Villegas, Macdiel Acevedo-Quiroz, R. Razo‐Hernández, P. Álvarez-Fitz, M. Mendoza-Catalán, Vojetch Jancik, R. Cea-Olivares (2020)
Synthesis, crystal structure, antibacterial, antiproliferative and QSAR studies of new bismuth(III) complexes of pyrrolidineditiocarbamate of dithia-bismolane and bismane, oxodithia- and trithia-bismocaneJournal of Molecular Structure, 1217
Hong-Xing Zheng, Xiang-Huan Shan, Jian-Ping Qu, Yan-Biao Kang (2018)
Strategy for Overcoming Full Reversibility of Intermolecular Radical Addition to Aldehydes: Tandem C-H and C-O Bonds Cleaving Cyclization of (Phenoxymethyl)arenes with Carbonyls to Benzofurans.Organic letters, 20 11
Mingxue Li, Min Yang, J. Niu, Lizhi Zhang, Song-Qiang Xie (2012)
A nine-coordinated bismuth(III) complex derived from pentadentate 2,6-diacetylpyridine bis((4)N-methylthiosemicarbazone): crystal structure and both in vitro and in vivo biological evaluation.Inorganic chemistry, 51 22
Franca-Maria Klingler, T. Wichelhaus, Denia Frank, Jenifer Cuesta-Bernal, Jasmin El-Delik, H. Müller, H. Sjuts, S. Göttig, Arno Koenigs, K. Pos, D. Pogoryelov, E. Proschak (2015)
Approved Drugs Containing Thiols as Inhibitors of Metallo-β-lactamases: Strategy To Combat Multidrug-Resistant Bacteria.Journal of medicinal chemistry, 58 8
A. Luqman, V. Blair, Rajini Brammananth, P. Crellin, R. Coppel, P. Andrews (2014)
Homo- and heteroleptic bismuth(III/V) thiolates from N-heterocyclic thiones: synthesis, structure and anti-microbial activity.Chemistry, 20 44
A. Raheel, Imtiaz-ud-Din., Sohaila Andleeb, S. Ramadan, M. Tahir (2017)
Synthesis and structural characterization of new bioactive ligands and their Bi(III) derivatives: (pivaloylcarbamothioyl)amino acids and their bismuth(III) derivativesApplied Organometallic Chemistry, 31
I. Cota, Valentina Marturano, B. Tylkowski (2019)
Ln complexes as double faced agents: Study of antibacterial and antifungal activityCoordination Chemistry Reviews
F. Paladini, M. Pollini, A. Sannino, L. Ambrosio (2015)
Metal-Based Antibacterial Substrates for Biomedical Applications.Biomacromolecules, 16 7
Laiba Saleem, A. Altaf, A. Badshah, M. Rauf, A. Waseem, M. Danish, S. Azam, M. Arshad, Abdullah Asiri, Sajjad Ahmad, R. Gul (2018)
Structural investigations, anti-leishmanial, antibacterial and docking studies of new pentavalent antimony carboxylatesInorganica Chimica Acta, 474
H. Breunig, M. Nema, C. Silvestru, A. Soran, R. Varga (2010)
[2-{E(CH2CH2)2NCH2}C6H4]nBiX3–n (E = O, NMe; X = Cl, Br, I; n = 1–3) and [2-(Me2NCH2)C6H4]BiBr2 – New Hypervalent Organobismuth(III) Compounds†Zeitschrift für anorganische und allgemeine Chemie, 636
Chuan‐Hua Li, Jian‐Hong Jiang, Yan‐Hua Lei, Xu Li, Fei-Hong Yao, Mengting Ji, Kai Zhang, Li‐Ming Tao, L. Ye, Qiang‐Guo Li (2022)
Design, synthesis, and biological evaluation of dinuclear bismuth(III) complexes with Isoniazid-derived Schiff basesJournal of Inorganic Biochemistry
Sajjad Rakhshani, A. Rezvani, M. Dušek, V. Eigner (2018)
Design and synthesis of novel thiourea metal complexes with controllable antibacterial properties: NoApplied Organometallic Chemistry, 32
J. Salvador, Sandra Figueiredo, R. Pinto, S. Silvestre (2012)
Bismuth compounds in medicinal chemistry.Future medicinal chemistry, 4 11
A. Luqman, V. Blair, Rajini Brammananth, P. Crellin, R. Coppel, P. Andrews (2016)
The Importance of Heterolepticity in Improving the Antibacterial Activity of Bismuth(III) ThiolatesEuropean Journal of Inorganic Chemistry, 2016
D. Kowalczuk, M. Miazga-Karska, Agata Gładysz, Paweł Warda, A. Barańska, B. Drop (2020)
Characterization of Ciprofloxacin-Bismuth-Loaded Antibacterial Wound DressingMolecules, 25
Melissa Werrett, Megan Herdman, Rajini Brammananth, U. Garusinghe, W. Batchelor, P. Crellin, R. Coppel, P. Andrews (2018)
Bismuth Phosphinates in Bi-Nanocellulose Composites and their Efficacy towards Multi-Drug Resistant Bacteria.Chemistry, 24 49
Hongyan Li, Hongzhe Sun (2012)
Recent advances in bioinorganic chemistry of bismuthCurrent Opinion in Chemical Biology, 16
N. Yang, Hongzhe Sun (2007)
Biocoordination chemistry of bismuth : Recent advancesCoordination Chemistry Reviews, 251
Lan‐Qin Chai, Yong‐Mei Chai, Xiao‐Fang Zhang (2022)
Two mono‐ and dinuclear Bi (III) complexes combined with crystallographic, spectroscopic, antibacterial activities, MEP/HSA, and TD/DFT calculationsApplied Organometallic Chemistry
K. Iuchi, T. Yagura (2018)
Heterocyclic organobismuth (III) compounds containing an eight-membered ring: Inhibitory effects on cell cycle progression.Toxicology in vitro : an international journal published in association with BIBRA, 50
I. Ferreira, E. Piló, Angel Recio-Despaigne, J. Silva, J. Ramos, L. Marques, P. Prazeres, J. Takahashi, E. Souza-Fagundes, W. Rocha, H. Beraldo (2016)
Bismuth(III) complexes with 2-acetylpyridine- and 2-benzoylpyridine-derived hydrazones: Antimicrobial and cytotoxic activities and effects on the clonogenic survival of human solid tumor cells.Bioorganic & medicinal chemistry, 24 13
Yang Yang, Ruizhuo Ouyang, Li'na Xu, Ning Guo, Weiwei Li, Kai Feng, Ouyang Lei, Zhuoyuan Yang, Shuang Zhou, Y. Miao (2015)
Review: Bismuth complexes: synthesis and applications in biomedicineJournal of Coordination Chemistry, 68
Liam Stephens, Sarmishta Munuganti, Rebekah Duffin, Melissa Werrett, P. Andrews (2020)
Is Bismuth Really the "Green" Metal? Exploring the Antimicrobial Activity and Cytotoxicity of Organobismuth Thiolate Complexes.Inorganic chemistry
M. Mitcheltree, A. Pisipati, E. Syroegin, K. Silvestre, D. Klepacki, Jeremy Mason, D. Terwilliger, G. Testolin, A. Pote, Kelvin Wu, R. Ladley, K. Chatman, A. Mankin, Y. Polikanov, A. Myers (2021)
A synthetic antibiotic class overcoming bacterial multidrug resistanceNature, 599
R. Ge, Xuesong Sun, Q. Gu, R. Watt, J. Tanner, B. Wong, H. Xia, Jian-Dong Huang, Qing‐Yu He, Hongzhe Sun (2007)
A proteomic approach for the identification of bismuth-binding proteins in Helicobacter pyloriJBIC Journal of Biological Inorganic Chemistry, 12
R. Olar, M. Badea, M. Chifiriuc (2022)
Metal Complexes—A Promising Approach to Target Biofilm Associated InfectionsMolecules, 27
N. Tan, Yi Chen, Yongbo Zhou, C. Au, S. Yin (2013)
Synthesis and Structure of Organobismuth Chlorides and Triflates Containing (C,E)-Chelating Ligands (E=O, S) and Their Catalytic Application in the Allylation of Aldehydes with Tetraallyltin.ChemPlusChem, 78 11
P. Andrews, R. Ferrero, P. Junk, I. Kumar, Q. Luu, K. Nguyen, James Taylor (2010)
Bismuth(III) complexes derived from non-steroidal anti-inflammatory drugs and their activity against Helicobacter pylori.Dalton transactions, 39 11
Mingxue Li, Yanli Lu, Min Yang, Yanke Li, Lizhi Zhang, Songqiang Xie (2012)
One dodecahedral bismuth(III) complex derived from 2-acetylpyridine N(4)-pyridylthiosemicarbazone: synthesis, crystal structure and biological evaluation.Dalton transactions, 41 41
K. Iuchi, Yuji Tasaki, Sayo Shirai, H. Hisatomi (2020)
Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 125
Yuanyuan Ma, M. Wei, Xuepeng Wang, Li-Hua Jiang, Yanshi Xiong, Jia Cheng, Yan-Shu Tan, Xiangwen Liao, Jintao Wang (2022)
Synthesis and antibacterial against S. aureus of new ruthenium (II) polypyridine complexes containing pyrene groupsApplied Organometallic Chemistry
P. Andrews, M. Busse, G. Deacon, R. Ferrero, P. Junk, Katie Huynh, I. Kumar, Jonathan Maclellan (2010)
Structural and solution studies of phenylbismuth(III) sulfonate complexes and their activity against Helicobacter pylori.Dalton transactions, 39 40
Yongping Liu, Jiancun Lei, Li-Wen Tang, Yao Peng, C. Au, Yi Chen, S. Yin (2017)
Studies on the cytotoxicity and anticancer performance of heterocyclic hypervalent organobismuth(III) compounds.European journal of medicinal chemistry, 139
Hao-Sheng Lin, Il Jeon, Yingqian Chen, Xiao-Yu Yang, Takafumi Nakagawa, S. Maruyama, Sergei Manzhos, Y. Matsuo (2019)
Highly Selective and Scalable Fullerene-Cation-Mediated Synthesis Accessing Cyclo[60]fullerenes with Five-Membered Carbon Ring and Their Application to Perovskite Solar CellsChemistry of Materials
Zhuoyu Chen, Qinglu Zhou, R. Ge (2011)
Inhibition of fumarase by bismuth(III): implications for the tricarboxylic acid cycle as a potential target of bismuth drugs in Helicobacter pyloriBioMetals, 25
F. Zobi, Sara Sovari, N. Radaković, P. Roch, A. Crochet, A. Pavic (2021)
Combatting AMR: A molecular approach to the discovery of potent and non-toxic rhenium complexes active against C. albicans-MRSA co-infection.European journal of medicinal chemistry, 226
Runming Wang, Tsz-pui Lai, P. Gao, Hongmin Zhang, P. Ho, Patrick Woo, Guixing Ma, R. Kao, Hongyan Li, Hongzhe Sun (2018)
Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitorsNature Communications, 9
Xiaowen Zhang, Xiaowen Zhang, J. Xia, Hui Yan, S. Luo, S. Yin, C. Au, C. Au, W. Wong (2009)
Synthesis, structure, and in vitro antiproliferative activity of cyclic hypervalent organobismuth(III) chlorides and their triphenylgermylpropionate derivativesJournal of Organometallic Chemistry, 694
Apurva Pandey, E. Boros (2020)
Coordination Complexes to Combat Bacterial Infections: Recent Developments, Current Directions and Future Opportunities.Chemistry
T. Corrie, Liam Ball, C. Russell, G. Lloyd‐Jones (2017)
Au-Catalyzed Biaryl Coupling To Generate 5- to 9-Membered Rings: Turnover-Limiting Reductive Elimination versus π-Complexation.Journal of the American Chemical Society, 139 1
C. Raț, C. Silvestru, H. Breunig (2013)
Hypervalent organoantimony and -bismuth compounds with pendant arm ligandsCoordination Chemistry Reviews, 257
A. Luqman, V. Blair, Rajini Brammananth, P. Crellin, R. Coppel, P. Andrews (2015)
Powerful Antibacterial Activity of Phenyl‐Thiolatobismuth(III) Complexes Derived from OxadiazolethionesEuropean Journal of Inorganic Chemistry, 2015
M. Patra, G. Gasser, N. Metzler‐Nolte (2012)
Small organometallic compounds as antibacterial agents.Dalton transactions, 41 21
K. Iuchi, Y. Hatano, T. Yagura (2008)
Heterocyclic organobismuth(III) induces apoptosis of human promyelocytic leukemic cells through activation of caspases and mitochondrial perturbation.Biochemical pharmacology, 76 8
C. Carmalt, A. Cowley, R. Culp, Richard Jones, S. Kamepalli, N. Norman (1997)
Synthesis and Structures of Intramolecularly Base-Coordinated Group 15 Aryl Halides.Inorganic chemistry, 36 13
A series of heterocyclic organobismuth (III) complexes based on bidentate C,O‐coordinating ligands were designed and synthesized as antimicrobials. Antibacterial assays showed that complexes of this type are more effective for Gram‐positive bacteria (Staphylococcus aureus, Staphylococcus epidermidis, and Enterococcus faecalis) than Gram‐negative ones (Escherichia coli and Pseudomonas aeruginosa). Their activities are especially relevant to the synergism of lipophilicity, geometry, and stability, which depends on both the identity of coordinating ligands and the coordination number at the bismuth center. By comparison, the hypervalent 14‐Bi‐6 species diarylbismuth nitrate (8) was found to exhibit the most potent inhibitory effect, together with a high degree of selectivity, which gives an IC50(LO2)/MIC(Staphylococcus aureus) ratio of up to 23.08. Time–kill analysis demonstrated that complex 8 is bacteriostatic at low concentrations while displaying significant bactericidal activity at high doses. The results of drug resistance experiments suggested that complex 8 can inhibit the formation of bacterial biofilm and consequently delay or prevent the development of drug resistance. Furthermore, complex 8 also showed high inhibition efficiency against several drug‐resistant Staphylococcus aureus, and the MIC values are within the range of 0.39–1.56 μM, thus indicating the lack of cross‐resistance between this organometallic compound and commonly used antibiotics.
Applied Organometallic Chemistry – Wiley
Published: Aug 1, 2023
Keywords: antibacterial; bidentate C,O‐coordinating ligands; cytotoxicity; hypervalent molecules; organobismuth
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