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AACN Advanced Critical Care Volume 26 , Number 3 , pp. 225 - 230 © 2015 AACN Antimicrobial Resistance Thinking Outside the Box Nancy Munro , RN, MN, CCRN, ACNP-BC ABSTRACT The health care system is challenged by ance. One challenge in that plan is to better another serious issue: antimicrobial resist- understand how microbes have become ance. Clostridium difficile is the most common resistant. Microbes have developed defense infection in health care institutions and is mechanisms such as bacteriophages and bac- becoming resistant to standard treatment. teriocins to survive for thousands of years. If Carbapenem-resistant enterobacteriaceae can science can start to use these mechanisms to be found in almost every state in the United help combat resistant organisms in combination States. Confounding the antimicrobial resist- with antimicrobials and strong epidemiological ance issue is the fact that few new antimicrobi- interventions, the battle against antimicrobial als are being developed by pharmaceutical resistance may succeed. companies. The situation is so critical that the Keywords: antimicrobial resistance , bacteri- White House issued a strategic plan in Sep- tember 2014 to deal with antimicrobial resist- ocins , bacteriophages 4(p2) ntimicrobial resistance patterns in bacte- long as we use antibiotics.” Drug-resistant Aria, fungi,
AACN Advanced Critical Care – Wolters Kluwer Health
Published: Jul 1, 2015
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