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Methodological overview of the NIMH Multisite Trial S1 Methodological overview of the NIMH Multisite HIV Prevention Trial for populations at risk for HIV adopted by the public health system and tailored to the Introduction needs of local populations at r isk for HIV. NIMH staff developed a concept for the multisite study that received The National Institute of Mental Health (NIMH) Multi- site HIV Prevention Trial is the first randomized, con- an external scientific review. A request for applications trolled, multisite, multiple population, group HIV preven- was developed, and seven sites and one coordinating center tion study conducted in the United States. The trial were selected to design and conduct the tr ial. Following addressed two pressing public health needs. The first was pilot work with different populations, the research team developed a detailed trial protocol. the immediate need for a carefully evaluated HIV preventive intervention that could be used by service providers with clients at risk for HIV infection. The second was the need for a behavioral intervention that could be Objectives of the trial used in combination with a prophylactic vaccine efficacy trial. Participants in this trial were among those individuals The primary objective of the NIMH
AIDS, Supplement – Wolters Kluwer Health
Published: Feb 1, 1997
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